Results 101 to 110 of about 15,210 (215)

LongITools:dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases

, 2022
The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments.
van Enckevort, E. (Esther), Keikkala, E. (Elina), Kavousi, M. (Maryam), Kolehmainen, M. (Marjukka), Heiskala, A. (Anni), Voortman, T. (Trudy), Lekadir, K. (Karim), Jaddoe, V. W. (Vincent W. V.), Ulven, S. M. (Stine M.), Wright, T. (Thomas), Kerckhoffs, J. (Jules), Mortari, A. P. (Andrea Piano), Timpson, N. (Nicholas), Haakma, S. (Sido), Belotti, F. (Federico), Hoek, G. (Gerard), d'Amico, E. (Enrico), Zarei, I. (Iman), Vääräsmäki, M. (Marja), Atella, V. (Vincenzo), Soares, A. G. (Ana Goncalves), Heil, K. F. (Katharina F.), Kaakinen, M. A. (Marika A.), Parusso, S. (Stefano), Charles, M.-A. (Marie-Aline), Matthews, J. (Jason), Swertz, M. (Morris), Nedelec, R. (Rozenn), Hyde, E. (Eleanor), Savolainen, O. (Otto), de Rooij, S. R. (Susanne R.), Näätänen, M. (Mari), Eadie, N. d. (Nina de Toro), Chadeau-Hyam, M. (Marc), Motoc, I. (Irina), Bulgheroni, M. (Maria), Cascarano, A. (Anna), Klavus, A. (Anton), Järvelin, M.-R. (Marjo-Riitta), Lakka, T. (Timo), Hanhineva, K. (Kati), Conti, G. (Gabriella), Simonetti, V. (Valentina), Prokopenko, I. (Inga), Evans, J. (Jayne), Lepeule, J. (Johanna), Tzala, E. (Evangelia), Gaillard, R. (Romy), Atehortua, A. (Angelica), Juola, T. (Teija), Jacquemin, B. (Benedicte), Felix, J. F. (Janine F.), Elhakeem, A. (Ahmed), Kopinska, J. A. (Joanna A.), Ulrich, A. (Anna), Heude, B. (Barbara), Ronkainen, J. (Justiina), Holven, K. B. (Kirsten B.), Zins, M. (Marie), Kajantie, E. (Eero), Castleton, C. (Christopher), Sebert, S. (Sylvain), Marazzi, F. (Francesca), Brunius, C. (Carl), Landberg, R. (Rikard), Roseboom, T. (Tessa), Halonen, M. (Miia), Webster, C. (Claire), Vermeulen, R. (Roel), Rundblad, A. (Amanda), Balkhiyarova, Z. (Zhanna), Ribbenstedt, A. (Anton)   +71 more
core  

Sequencing the exposome: A call to action

Toxicology Reports, 2016
The exposome is a complement to the genome that includes non-genetic causes of disease. Multiple definitions are available, with salient points being global inclusion of exposures and behaviors, and cumulative integration of associated biologic responses.
Dean P. Jones
doaj   +1 more source

Precision residential greenspace, urban environmental exposures, and incident dementia among older adults in Sweden: A 16‐year cohort study

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Residential greenspace is linked to mental and cardiometabolic health, but longitudinal studies on detailed greenspace and dementia incidence are limited. METHODS We followed 2993 dementia‐free participants in the Swedish National Study on Aging and Care Kungsholmen for 16 years; 477 developed clinically diagnosed dementia ...
Cecilia U. D. Stenfors, Jing Wu, Giulia Grande, Andrei Pyko, Mare Löhmus, Göran Pershagen, Debora Rizzuto   +6 more
wiley   +1 more source

A general exposome factor explains individual differences in functional brain network topography and cognition in youth

Developmental Cognitive Neuroscience
Childhood environments are critical in shaping cognitive neurodevelopment. With the increasing availability of large-scale neuroimaging datasets with deep phenotyping of childhood environments, we can now build upon prior studies that have considered ...
Arielle S. Keller, Tyler M. Moore, Audrey Luo, Elina Visoki, Mārtiņš M. Gataviņš, Alisha Shetty, Zaixu Cui, Yong Fan, Eric Feczko, Audrey Houghton, Hongming Li, Allyson P. Mackey, Oscar Miranda-Dominguez, Adam Pines, Russell T. Shinohara, Kevin Y. Sun, Damien A. Fair, Theodore D. Satterthwaite, Ran Barzilay   +18 more
doaj   +1 more source

Integrating exposomics into biomedicine

Science
Assessing a full range of environmental exposures will improve human ...
Miller, Gary W, Bennett, L Michelle, Balshaw, David, Barouki, Robert, Bhutani, Gurdane, Dolinoy, Dana, Gao, Peng, Jett, David, Karagas, Margaret, Klánová, Jana, Lein, Pamela, Li, Shuzhao, Metz, Thomas O, Patel, Chirag J, Pollitt, Krystal, Rajasekar, Arcot, Sillé, Fenna, Thessen, Anne, Thuault-Restituito, Sophie, Vermeulen, Roel, Ward-Caviness, Cavin K, Wright, Robert   +21 more
openaire   +3 more sources

The AD Exposome

International Journal of Biomedical Science, 2023
Efforts to find human genes for Alzheimer Disease and for longevity have generally neglected environmental influences. Brain aging and ADRDA may be understood in the AD Exposome framework, which includes external and endogenous interactions from embryo to old age (Finch and Kulminski 2019; Finch and Haghani 2021).
openaire   +1 more source

Lifestyle differences between co-twins are associated with decreased similarity in their internal and external exposome profiles

Scientific Reports
Whether differences in lifestyle between co-twins are reflected in differences in their internal or external exposome profiles remains largely underexplored.
Gabin Drouard, Zhiyang Wang, Aino Heikkinen, Maria Foraster, Jordi Julvez, Katja M. Kanninen, Irene van Kamp, Matti Pirinen, Miina Ollikainen, Jaakko Kaprio   +9 more
doaj   +1 more source

Exposome‐wide association study and predictive risk score for incident Alzheimer's disease and related dementias

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Environmental exposures contribute substantially to Alzheimer's disease and related dementias (ADRD), yet comprehensive exposome‐wide investigations systematically evaluating multi‐domain environmental factors remain limited and lacking utility for precision medicine. METHODS We conducted an exposome‐wide association study (ExWAS)
Chenshuang Li, Chenxu Zhao, Yiqun Lan, Randall J Ellis, Shakson Isaac, Sai Zhang, Gary W. Miller, Yi Sun, Shalini Jain, Hariom Yadav, Peng Gao, Chirag J Patel   +11 more
wiley   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 26-47, October 2026.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

Science of omics: a molecular space odyssey

Experimental Physiology, EarlyView.
Salomé Coppens, Christophe Hirtz, Margaux Vignon, Damian M. Bailey   +3 more
wiley   +1 more source