Results 81 to 90 of about 15,210 (215)

Trans‐resveratrol alleviates inflammation and improves skin barrier function via aryl hydrocarbon receptor pathway in human reconstructed epidermis

International Journal of Cosmetic Science, EarlyView.
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff, Sandeep Keshavan, Regina G. Daré, Alke Petri‐Fink, Marc Eeman, Agnès Tessier, Barbara Rothen‐Rutishauser   +6 more
wiley   +1 more source

Drug Repurposing for Parkinson's Disease Prevention: Replication Study of Three Drugs in French Healthcare Databases

Movement Disorders, EarlyView.
Yanis Saidi, Anne Paakinaho, Eeva Pylkkö, Sirpa Hartikainen, Anna‐Maija Tolppanen, Alexis Elbaz, Ismaïl Ahmed, Anne C.M. Thiébaut, Émeline Courtois   +8 more
wiley   +1 more source

Environmental and lifestyle determinants of skin ageing: Association between skin dryness and dyspigmentation in Chinese women

International Journal of Cosmetic Science, EarlyView.
The study of photoageing visible features in an Asian female cohort from rural and urban locations and across seasons evidenced a consistent correlation between skin dyspigmentation and dryness, suggesting mechanistic interplay, and emphasizing that these key concerns of ageing skin could be addressed more efficiently taken together.
Judith Elkaim, Robin Kurfurst, Gallic Beauchef, Tianxiang Ouyang, Catherine Heusèle, Sylvianne Schnebert, Karl Pays, Carine Nizard   +7 more
wiley   +1 more source

Exposome and allostatic load

, 2023
The concept of allostatic load (AL) (McEwen 2000) captures the biological burden that stress imposes on an individual over time. This project will test the relationship between stress exposure as modeled by the total exposome scores we have previously ...
Ran Barzilay, Tyler Maxwell Moore, Kevin Hoffman   +2 more
core   +1 more source

Annual Research Review: Sex differences in conduct disorder – revisiting existing evidence and exploring future directions

Journal of Child Psychology and Psychiatry, EarlyView.
Conduct disorder (CD) is a common psychiatric disorder in youth, characterized by severe and recurrent aggressive and antisocial behaviors and associated with substantial healthcare and societal costs. Rates of CD increase during adolescence in both sexes, with the male‐to‐female ratio narrowing to approximately 1:1.
Anka Bernhard, Christine M. Freitag, Kerstin Konrad, Lucres Jansen, Andreas G. Chiocchetti, Christina Stadler, Stephane A. De Brito, Graeme Fairchild, Gregor Kohls   +8 more
wiley   +1 more source

Applying hair exposome for linking environmental exposure to reproductive health: A comprehensive review and research perspective

Hygiene and Environmental Health Advances
Increasing evidences have revealed a close relationship between various environmental exposures and reproductive health. The real-world complex exposure scenario along with intricate interactions effects of these exposures has high demands of exposome ...
Mengyuan Ren, Mingliang Fang, Jing Liu, Qun Lu, Hongchu Bao, Lili Zhuang, Fangang Meng, Bo Pan, Lailai Yan, Zhiwen Li, Jia Xu, Bin Han, Zhipeng Bai, Chan Tian, Ying Wang, Bin Wang   +15 more
doaj   +1 more source

The exposome concept: a challenge and a potential driver for environmental health research

European Respiratory Review, 2016
The exposome concept was defined in 2005 as encompassing all environmental exposures from conception onwards, as a new strategy to evidence environmental disease risk factors. Although very appealing, the exposome concept is challenging in many respects.
Valérie Siroux, Lydiane Agier, Rémy Slama   +2 more
doaj   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

MetFrag: Annotating "Unknowns" - Exposome Boot Camp 2020 Virtual Edition [PDF]

, 2020
The 2020 edition of the Exposome Boot Camp run by the Columbia University Mailman School of Public Health will be held online due to the current world situation. Further details are on the website.
SCHYMANSKI, Emma
core   +1 more source

Identification of exposome clusters based on societal, social, built and natural environment – results of the ABCD cohort study

Environment International
Exposome research has seen a recent increase. The conceptual framework of the Social Exposome extends initial concepts by considering the entirety of societal, social, built and natural environmental exposures which are assumed to holistically impact ...
Klaus Telkmann, Helene Gudi-Mindermann, Rik Bogers, Jenny Ahrens, Justus Tönnies, Irene van Kamp, Tanja Vrijkotte, Gabriele Bolte   +7 more
doaj   +1 more source