Results 61 to 70 of about 17,412 (233)

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

Association of cumulative early medical events and neurodevelopmental conditions through a common latent factor—A population‐based twin study

JCPP Advances, EarlyView.
Abstract Background The cumulative effect of early medical events has been shown to be associated with autism. It is unclear whether this effect is specific to autism or if it is associated to other neurodevelopmental conditions (NDCs) as well. Methods We established a registry‐linked population‐based twin cohort of 10,254 pairs within the child and ...
Torkel Carlsson, Henrik Larsson, Sebastian Lundström, Sven Bölte, Mark J. Taylor   +4 more
wiley   +1 more source

The influence of exposome on acne [PDF]

Journal of the European Academy of Dermatology and Venereology, 2018
AbstractBackgroundAcne vulgaris is one of the main reasons for dermatological consultations. Severity and response to treatment may be impacted by various external factors or exposome.AimTo assess the impact of environmental factors on acne and to provide a comprehensive overview of the acne exposome.MethodsTwo consensus meetings of five European ...
Dréno, Brigitte, Bettoli, Vincenzo, Araviiskaia, Elena, Sanchez Viera, Miguel, Bouloc, Anne   +4 more
openaire   +4 more sources

Mapping the Urban Lead Exposome: A Detailed Analysis of Soil Metal Concentrations at the Household Scale Using Citizen Science [PDF]

, 2018
An ambitious citizen science effort in the city of Indianapolis (IN, USA) led to the collection and analysis of a large number of samples at the property scale, facilitating the analysis of differences in soil metal concentrations as a function of ...
Adamic, Jessica, Filippelli, Gabriel M., Frix, Emeline, Nichols, Deborah, Shukle, John   +4 more
core   +2 more sources

Evaluating the combined toxicity of Penicillium mycotoxins in absorption, metabolism, and excretion systems

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Penicillium mycotoxins, including ochratoxin A (OTA), citrinin (CIT), and cyclopiazonic acid (CPZ), frequently co‐occur in food commodities, contributing to chronic low‐level dietary exposure. However, current risk assessments often consider these toxins individually, overlooking potential interaction effects.
Carolina Sousa Monteiro, Eugénia Pinto, Miguel A Faria, Sara C Cunha   +3 more
wiley   +1 more source

Redox biology: Interface of the exposome with the proteome, epigenome and genome

Redox Biology, 2014
The exposome is the cumulative measure of environmental influences and associated biological responses throughout lifespan, including exposures from the environment, diet, behavior and endogenous processes. Much of the direct interaction of an individual′
Young-Mi Go, Dean P. Jones
doaj   +1 more source

Parental, prenatal, and neonatal associations with ball skills at age 8 using an exposome approach. [PDF]

, 2014
There is little consistency in the literature concerning factors that influence motor coordination in children. A hypothesis-free "exposome" approach was used with 7359 children using longitudinal information covering 3 generations in regard to throwing ...
Davis, John M, Emmett, Pauline, Golding, Jean, Gregory, Steven, Hibbeln, Joseph R, Iles-Caven, Yasmin, Lingam, Raghu, Steer, Colin D   +7 more
core   +3 more sources

Startups Driving Artificial Intelligence Into Clinical Dermatology

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transitioning from innovation to routine clinical application in dermatology. This review examines how AI‐enabled technologies are being developed and integrated across diverse clinical purposes and workflows.
Dominique Du Crest, Benjamin Miguel Monteagudo, Stanislas Vandier, Mullarkey Dan, Svedenhag Per, Jon Friis, Monisha Madhumita, Lilit Garibyan, Tu‐Anh Duong, Merete Haedersdal, Vinzent Kevin Ortner   +10 more
wiley   +1 more source

Neighborhood Deprivation and Voice and Reflux Symptom Burden in a Tertiary Laryngology Cohort

The Laryngoscope, EarlyView.
ABSTRACT Objective The voice handicap index‐10 (VHI‐10) and reflux symptoms index (RSI) are validated, patient‐reported outcome measures (PROMs) commonly used in laryngology to assess the subjective impact of voice disorders and severity of symptoms associated with laryngopharyngeal reflux, respectively.
Sandra Stinnett, Shirley X. Liu, Katie M. Carlson, Leah Helou, Libby Smith, Chloe Santa Maria, Angela L. Mazul   +6 more
wiley   +1 more source

On the road to personalised and precision geomedicine: medical geology and a renewed call for interdisciplinarity [PDF]

, 2016
Our health depends on where we currently live, as well as on where we have lived in the past and for how long in each place. An individual’s place history is particularly relevant in conditions with long latency between exposures and clinical ...
Kamel Boulos, MN, Le Blond, JS
core   +2 more sources