Results 101 to 110 of about 3,965,960 (305)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Measurement Error in Exposure Assessment: An Error Model and its Impact on Studies on Lung Cancer and Residential Radon Exposure in Germany [PDF]

open access: yes, 2002
Case-control studies on lung cancer and residential radon exposure had been conducted in Germany. Relative risk estimates from primary analysis were now subject to accounting for uncertainties in radon exposure and in the most potent confounder smoking.
Heid, Iris
core   +1 more source

MAJOR OUTCOMES OF THE WORK PERFORMED BY ST. PETERSBURG RESEARCH INSTITUTE OF RADIATION HYGIENE AFTER PROFESSOR P. V. RAMZAEV ON THE IMPLEMENTATION OF THE FEDERAL TARGETED PROGRAM “MITIGATION OF THE RADIATION ACCIDENTS’CONSEQUENCES UNTIL 2015” AND OF THE “JOINT ACTIVITIES PROGRAM ON MITIGATION OF THE CHERNOBYL DISASTER WITHIN THE UNION STATE FOR THE PERIOD UNTIL 2016“

open access: yesРадиационная гигиена, 2016
The article presents major results of the work performed by St. Petersburg Research Institute of Radiation Hygiene after Professor P. V. Ramzaev on public contracts signed within the implementation of the Federal targeted program “ Mitigation of the ...
A. N. Barkovskiy   +3 more
doaj  

Derivation of the oral reference dose (RfD) for bisphenol S and bisphenol F based on epidemiological and experimental studies

open access: yesEcotoxicology and Environmental Safety
With bisphenol A (BPA) restricted, its analogs are appearing frequently in the environment, raising health concerns. However, no reasonable threshold of toxicity has been established at the current international level for BPA analogs.
Jing Cao   +4 more
doaj   +1 more source

Indoor radon levels and total gamma dose rates measurements in Portuguese thermal spas

open access: yesInternational Journal of Occupational and Environment Safety, 2017
In this study, an assessment of indoor radon concentration and gamma dose rates were carried out in 16 Portuguese thermal spas. Indoor gamma dose rates measurements were made using a Geiger counter (Gamma Scout – GS3) and radon concentration ...
A. S. Silva, M. L. Dinis
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

RADIATION AND HEALTH: REFLECTIONS OF PHYSICIAN-EXPERT

open access: yesРадиационная гигиена, 2015
The main difficulties at an assessment of connection of a clinical syndrome with radiation exposure are analyzed. Most simply the problem is solved for connection of the determined effects with radiation exposure especially for the time periods shortly ...
A. K. Gus’kova
doaj  

Evaluation of Factors Affecting Absorbed Dose, Optimization Methods and Patient Dose Reduction in Dental Cone Beam CT (CBCT)

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Nowadays the use of cone beam computed tomography in dental imaging is increasing, although this method has a much lower dose than conventional CT scans, it delivers a higher dose than the panoramic and periapical patients therefore, , the ...
Azam Asgari   +3 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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