Results 1 to 10 of about 5,546,459 (287)

In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche

open access: yesNature Communications, 2021
Short term systemic expression of the reprogramming factors Oct-3/4, Sox2, Klf4, c-Myc (OSKM) rejuvenates aging cells and promotes tissue regeneration.
Chao Wang   +14 more
doaj   +1 more source

Immunohistochemical Expression [PDF]

open access: yesApplied Sciences, 2021
Immunohistochemistry (IHC) is an ancillary method, widely used in pathologist practice, that allows to identify diagnostic and prognostic/predictive therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of the antibody–antigene binding complex ...
Loreto C., Caltabiano R.
openaire   +3 more sources

Genome-wide binding potential and regulatory activity of the glucocorticoid receptor’s monomeric and dimeric forms

open access: yesNature Communications, 2021
Glucocorticoid receptors (GR) are thought to bind DNA as dimers or monomers, to regulate different transcription pathways. Here, the authors perform genome-wide studies on GRs with mutations that impair dimerization and provide evidence that monomeric ...
Thomas A. Johnson   +4 more
doaj   +1 more source

Virtualización Integral de Asignaturas de Expresión Gráfica en los Grados de Ingeniería = Comprehensive Virtualization of Graphic Expression Subjects in Engineering Degrees

open access: yesAdvances in Building Education, 2021
El principal objetivo de este trabajo ha sido la virtualización de diferentes asignaturas del departamento de Expresión Gráfica de la Escuela de Ingenierías Industriales, entre las que se encuentran: Instalaciones Industriales y Comerciales II ...
Juan Pablo Carrasco-Amador   +5 more
doaj   +1 more source

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

open access: yesNature Communications, 2020
Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao   +11 more
doaj   +1 more source

Acute deletion of TET enzymes results in aneuploidy in mouse embryonic stem cells through decreased expression of Khdc3

open access: yesNature Communications, 2022
Inducible disruption of TET dioxygenases in mouse embryonic stem cells results in chromosome mis-segregation and aneuploidies, due to Khdc3 downregulation suggesting a role for TET enzymes and DNA methylation patterns in maintaining genome stability.
Romain O. Georges   +8 more
doaj   +1 more source

RGmatch: matching genomic regions to proximal genes in omics data integration

open access: yesBMC Bioinformatics, 2016
Background The integrative analysis of multiple genomics data often requires that genome coordinates-based signals have to be associated with proximal genes.
Pedro Furió-Tarí   +2 more
doaj   +1 more source

Expression Conditional Gan for Facial Expression-to-Expression Translation [PDF]

open access: yes2019 IEEE International Conference on Image Processing (ICIP), 2019
5 pages, 5 figures, accepted to ICIP ...
Tang H.   +6 more
openaire   +2 more sources

Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells [version 1; referees: 2 approved, 1 approved with reservations]

open access: yesWellcome Open Research, 2018
Background: Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular
Tony Ly   +6 more
doaj   +1 more source

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

open access: yesPeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun   +5 more
doaj   +2 more sources

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