Results 1 to 10 of about 5,546,459 (287)
Short term systemic expression of the reprogramming factors Oct-3/4, Sox2, Klf4, c-Myc (OSKM) rejuvenates aging cells and promotes tissue regeneration.
Chao Wang +14 more
doaj +1 more source
Immunohistochemical Expression [PDF]
Immunohistochemistry (IHC) is an ancillary method, widely used in pathologist practice, that allows to identify diagnostic and prognostic/predictive therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of the antibody–antigene binding complex ...
Loreto C., Caltabiano R.
openaire +3 more sources
Glucocorticoid receptors (GR) are thought to bind DNA as dimers or monomers, to regulate different transcription pathways. Here, the authors perform genome-wide studies on GRs with mutations that impair dimerization and provide evidence that monomeric ...
Thomas A. Johnson +4 more
doaj +1 more source
El principal objetivo de este trabajo ha sido la virtualización de diferentes asignaturas del departamento de Expresión Gráfica de la Escuela de Ingenierías Industriales, entre las que se encuentran: Instalaciones Industriales y Comerciales II ...
Juan Pablo Carrasco-Amador +5 more
doaj +1 more source
Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao +11 more
doaj +1 more source
Inducible disruption of TET dioxygenases in mouse embryonic stem cells results in chromosome mis-segregation and aneuploidies, due to Khdc3 downregulation suggesting a role for TET enzymes and DNA methylation patterns in maintaining genome stability.
Romain O. Georges +8 more
doaj +1 more source
RGmatch: matching genomic regions to proximal genes in omics data integration
Background The integrative analysis of multiple genomics data often requires that genome coordinates-based signals have to be associated with proximal genes.
Pedro Furió-Tarí +2 more
doaj +1 more source
Expression Conditional Gan for Facial Expression-to-Expression Translation [PDF]
5 pages, 5 figures, accepted to ICIP ...
Tang H. +6 more
openaire +2 more sources
Background: Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular
Tony Ly +6 more
doaj +1 more source
Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun +5 more
doaj +2 more sources

