Results 21 to 30 of about 5,546,459 (287)
Producing recombinant proteins in Vibrio natriegens
Microbial Cell FactoriesThe diversity of chemical and structural attributes of proteins makes it inherently difficult to produce a wide range of proteins in a single recombinant protein production system.
Matthew Smith +26 more
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Children, 2021 Physical Education is one of the subjects that arouses the most interest in children. The aim of this study is to find out the opinion that primary school students have about the Physical Education class.
Javier Cachón-Zagalaz +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale +6 more
wiley +1 more source
npj Breast Cancer, 2017 Stem cells: protein not needed for stem cell activity in mammary gland A protein considered necessary for mammary stem cell activity turns out to be dispensable. What’s more, it’s not required for tumor development either.
Christy L. Trejo +4 more
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ISPRS International Journal of Geo-Information, 2021 Suitable graphic documentation is essential to ascertain and conserve architectural heritage. For the first time, accurate digital images are provided of a 16th-century wooden ceiling, composed of geometric interlacing patterns, in the Pinelo Palace in ...
Juan Francisco Reinoso-Gordo +2 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein +3 more
wiley +1 more source
SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells
Nature Communications, 2018 The mechanism of resistance to EZH2 inhibitors in cancers with inactivating SWI/SNF mutations is unknown. Here, the authors demonstrate that the switch of the SWI/SNF catalytic subunits from SMARCA4 to SMARCA2 drives resistance to EZH2 inhibitors in ...
Shuai Wu +11 more
doaj +1 more source
Sensors, 2020 In the work environment, there are usually different pathologies that are related to Repetitive Efforts and Movements (REM) that tend to predominantly affect the upper limbs.
Dolores Parras-Burgos +4 more
doaj +1 more source
Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus +6 more
wiley +1 more source
Loss of TET2 and TET3 in regulatory T cells unleashes effector function
Nature Communications, 2019 Loss of TET proteins in immune cell populations is known to result in immunopathology. Here the authors show that deficiency of Tet2 and Tet3 proteins, specifically in the CD4+ FoxP3+ Treg lineage, results in a dominant pathology in which ex-Treg cells ...
Xiaojing Yue +4 more
doaj +1 more source