Results 151 to 160 of about 3,394,943 (264)

Unique Regulation of Sed-1 β-Lactamase in Citrobacter sedlakii: Insights on Resistance to Third-Generation Cephalosporin

Antibiotics
Background: The Citrobacter genus harbors class C (AmpC) and class A β-lactamases. Citrobacter freundii produces an inducible AmpC β-lactamase controlled by the LysR-type transcriptional regulator AmpR and cytosolic amidase AmpD.
Mako Watanabe, Ryuichi Nakano, Keizo Yamamoto, Akiyo Nakano, Yuki Suzuki, Kai Saito, Satoko Nakashima, Kentaro Endo, Kazuya Narita, Hisakazu Yano   +9 more
doaj   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier, Morten Hylander Møller, Maj‐Brit Nørregaard Kjær, Fredrik Sjövall, Marie Warrer Munch, Benjamin Skov Kaas‐Hansen, Hans‐Christian Thorsen‐Meyer, Bodil Steen Rasmussen, Marie Helleberg, Frederik Boëtius Hertz, Theis Lange, Aksel Karl Georg Jensen, Lars Wiuff Andersen, Jakob Steen Andersen, Jens Michelsen, Lars Peter Kloster Andersen, Morten Heiberg Bestle, Anne Craveiro Brøchner, Theis Skovsgaard Itenov, Steffen Christensen, Ronni Thermann Reitz Plovsing, Klaus Ulrik Koch, Anders Møller, Olav Lilleholt Schjørring, Naia Bech Cranø, Kasper Vamdrup‐Andersen, Davide Placido, Tine Sylvest Meyhoff, Carl Thomas Anthon, Aske Tøgern, Milda Grigonyte‐Daraskeviciene, Zemira Engbakken, Anne Witte Kamstrup, Kis Rønn Uhre, Jehad Ahmad Barakji, Rikke Faebo Larsen, Anders Perner, Anders Granholm   +37 more
wiley   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, Volume 101, Issue 10, Page 2672-2676, October 2026.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

European Journal of Haematology, Volume 117, Issue 4, Page 1061-1071, October 2026.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen, Alexander Djupnes Fuglkjær, Tarec Christoffer El‐Galaly, Paw Jensen, Izabela Ewa Nielsen, Laurids Østergaard Poulsen, Mikkel Runason Simonsen, Kirstine Kobberøe Søgaard   +7 more
wiley   +1 more source

Genomic Medicine Sweden: Advancing precision medicine at the national level

Journal of Internal Medicine, Volume 300, Issue 4, Page 397-419, October 2026.
Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö, Anna Lindstrand, Panagiotis Baliakas, David Gisselsson, Paula Mölling, Mia Wadelius, Åsa Johansson, Hannes Olauson, Hans Ehrencrona, Lovisa Lovmar, Christian G. Giske, Henrik Green, Ann Nordgren, Fulya Taylan, Martin Hallbeck, Erika Tång Hallbäck, Anna Green, Markus Heidenblad, Kina Höglund, Anders Jemt, Carl Mårten Lindqvist, Maria Johansson Soller, Magnus Sabel, Colum Walsh, Hartmut Vogt, Craig E. Wheelock, Martin Bergö, Jens Enoksson, Ann Ekberg Jansson, Cecilia Fagerström, Jan Holgersson, Stephanie Anja Juran, Mats G. Karlsson, Frida Lundmark, Eva Tiensuu Janson, Andreas Muranyi Scheutz, Malin Sund, Päivi Östling, Sofia Gruvberger‐Saal, Marene Landström, Malin Melin, Lars Palmqvist, Richard Palmqvist, Bianca Stenmark, Anna Wedell, Malin Karnå, Katarina Nyström, Tobias Strid, Per Sikora, Maria Johansson, Therese Fagerqvist, Mirja Carlsson Möller, Oskar Frisell, Mats Ulfendahl, Mikaela Friedman, Lucia Cavelier, Valtteri Wirta, Thoas Fioretos, Richard Rosenquist   +58 more
wiley   +1 more source

AI‐Assisted SERS in Bacterial Diagnosis and Antimicrobial Susceptibility Testing: Advances, Gaps, and Translational Pathways

Advanced Sensor Research, Volume 5, Issue 9, September 2026.
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu, Yu Liu, Junlu Wang, Yujie Liu, Qijia Zhan, Jiangang Liu, Ruoping Chen, Kun Zhang   +7 more
wiley   +1 more source

Synthesis, Characterization, and Multifunctional Bioactivity of ZnO/CuO@Amoxicillin Nanocomposites: A Synergistic Nano‐Platform With Potent Antioxidant, Anti‐Inflammatory, Antidiabetic, and Anti‐Cholinesterase Activities

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ZnO/CuO@amoxicillin nanocomposite, synthesized via sol–gel route, demonstrates exceptional multifunctional performance. It strongly inhibits α‐amylase and α‐glucosidase, effectively suppresses inflammation, and exhibits superior antioxidant activity surpassing ascorbic acid.
Hocine Sadam Nesrat, Abdelatif Aouadi, Ibtissam Laib, Salah Eddine Laouini, Abderrhmane Bouafia, Djamila Hamada Saoud, Halima Zidane, Hafidha Terea, Mahmood M. S. Abdullah, Tomasz Trzepieciński, Dalila Saidane‐Mosbahi   +10 more
wiley   +1 more source

Susceptibility of extended-spectrum- β-lactamase-producing Escherichia coli to commercially available and laboratory-isolated bacteriophages.

, 2014
Extended-spectrum b-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E), particularly Escherichia coli and Klebsiella pneumoniae, are resistant to b-lactam antibiotics, b-lactam combinations and often non-b-lactam antibiotics.
Liam Burke (7212758), Mzia Kutateladze (7934708), Maia Ryan (7934702), Niall Stevens (7895957), Lika Leshkasheli (7934699), Nana Balarjishvili (7934696), Deirdre Fitzgerald Hughes (7895360), Darajen Bolkvadze (7934693), Hilary Humphreys (7895573)   +8 more
core   +2 more sources

A Thiosemicarbazone Schiff Base and Its Titanium(IV) Complexes: Spectral Analysis, DFT Studies, and Biological Evaluation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
DFT computations are used to analyze the electronic structure, stability, and reactivity profiles of a new Schiff base ligand and its Ti(IV) complexes and are characterized by elemental analysis, IR, 1H NMR, 13C NMR, and mass spectrometry and screened for antimicrobial activities against E. coli, S. aureus, ESBL, MRSA, Mtb, A.
Priyanka Ghanghas, Anshul Yadav, Astha Kamboj, Anita Choudhary, Manjinder Kour, Dinesh Kumar, Kavita Poonia   +6 more
wiley   +1 more source

Prevalence of Extended-Spectrum β-Lactamase and AmpC β-Lactamase among Clinical Isolates of Klebsiella pneumoniae

Journal of Pure and Applied Microbiology
Klebsiella pneumoniae (K. pneumoniae) is a high-priority antibiotic-resistant pathogen contributing significantly to the global burden of antimicrobial resistance (AMR).
P Chethankumar, Vidyavathi B. Chitharagi, Ranjitha Shankare Gowda, Sowmya G.S, Rashmi P. Mahale, Neetha S Murthy, Morubagal Raghavendra Rao, Wazea Abdualkader Hamood Al-Garadi   +7 more
doaj   +1 more source