Results 61 to 70 of about 3,394,943 (264)

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

Advanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao, Jun Sun, Liang Zhang, Litao Lin, Zongfeng Wan, Bingcai Pan, Sheng Tang   +6 more
wiley   +1 more source

Probing the Role of Asn 152 in the Class C β-lactamase AmpC [PDF]

, 2012
AmpC, a class C β-lactamase, is a main cause of antibiotic resistance to cephalosporins in many species of bacteria. The current proposed mechanism of action involves an acyl-intermediate, where the enzyme becomes covalently attached to the drug at ...
Powers, Rachel, Leonard, David, Anwar, Mujahid, Docter, Brianne, Wallar, Bradley   +4 more
core  

Table_1_Whole Genome Sequencing of Extended-Spectrum- and AmpC- β-Lactamase-Positive Enterobacterales Isolated From Spinach Production in Gauteng Province, South Africa.XLSX

, 2021
The increasing occurrence of multidrug-resistant (MDR) extended-spectrum β-lactamase- (ESBL) and/or AmpC β-lactamase- (AmpC) producing Enterobacterales in irrigation water and associated irrigated fresh produce represents risks related to the environment,
Stacey Duvenage (8714877), Lise Korsten (8714880), Mushal Allam (3497135), Arshad Ismail (9294066), Loandi Richter (8714871), Erika M. du Plessis (8714874)   +5 more
core   +1 more source

Whole genome sequencing of extended-spectrum β-lactamase producing Klebsiella pneumoniae isolated from a patient in Lebanon [PDF]

Frontiers in Cellular and Infection Microbiology, 2015
The emergence of extended-spectrum β-lactamase (ESBL)-producing bacteria is now a critical concern. The ESBL-producing Klebsiella pneumoniae constitutes one of the most common multidrug-resistant (MDR) groups of gram-negative bacteria involved in nosocomial infections worldwide.
Tokajian, Sima, Eisen, Jonathan A, Jospin, Guillaume, Farra, Anna, Coil, David A   +4 more
openaire   +5 more sources

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Integron-encoded GES-type extended-spectrum ß-lactamase with increased activity toward aztreonam in Pseudomonas aeruginosa [PDF]

, 2005
A Pseudomonas aeruginosa strain expresses an extended-spectrum β-lactamase, GES-9, which differs from GES-1 by a Gly243Ser substitution, is inhibited by clavulanic acid and imipenem, and hydrolyzes aztreonam.
Fortineau, N., Nordmann, P., Brinas, L., Poirel, L. [0000-0001-5160-5286]   +3 more
core   +1 more source

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

Extended-spectrum-β-lactamase-positive escherichia coli mainly adds to, rather than replaces, extended-spectrum-β-lactamase-negative e. coli in causing bacteraemia in hong kong, 2000-10

, 2012
Extended-spectrum-β-lactamase-positive escherichia coli mainly adds to, rather than replaces, extended-spectrum-β-lactamase-negative e.
PL Ho (6009764), KH Chow (17321398), Eric Lau (15903800), VCC Cheng (17321404), EL Lai (17321401)   +4 more
core   +1 more source

Carbapenem resistance in extensively drug-resistant Salmonella enterica serovar Agona and AmpC β-lactamase-producing S. Infantis

Microbiology Spectrum, 2023
We report that carbapenem resistance developed in an extensively drug-resistant Salmonella enterica serovar Agona strain during antimicrobial therapy and in an AmpC β-lactamase-producing S. Infantis strain.
Ping-Chun Hsu, You-Wun Wang, Bo-Han Chen, Yu-Ping Hong, Ru-Hsiou Teng, Po-Yu Liu, Chien-Shun Chiou   +6 more
doaj   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source