Results 41 to 50 of about 17,477 (250)

On Aggregation and Prediction of Cybersecurity Incident Reports

open access: yesIEEE Access, 2021
The study of cybersecurity incidents is an active research field. The purpose of this work is to determine accurate measures of cybersecurity incidents. An effective method to aggregate cybersecurity incident reports is defined to set these measures.
Miguel V. Carriegos   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decentralized Stability Enhancement of DFIG-Based Wind Farms in Large Power Systems: Koopman Theoretic Approach

open access: yesIEEE Access, 2022
This paper proposes a data-centric model predictive control (MPC) for supplemental control of a DFIG-based wind farm (WF) to improve power system stability.
Ahmed Husham   +3 more
doaj   +1 more source

Evaluation of the Region of Attractions of Higher Dimensional Hyperbolic Systems using the Extended Dynamic Mode Decomposition

open access: yesCoRR, 2022
This paper proposes an original methodology to compute the regions of attraction in hyperbolic and polynomial nonlinear dynamical systems using the eigenfunctions of the discrete-time approximation of the Koopman operator given by the extended dynamic mode decomposition algorithm.
Camilo Garcia-Tenorio   +3 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Identification of Dielectric Response Parameters of Pumped Storage Generator-Motor Stator Winding Insulation Based on Sparsity-Enhanced Dynamic Decomposition of Depolarization Current

open access: yesEnergies
Accurate diagnosis of the insulation condition of stator windings in pumped storage generator-motor units is crucial for ensuring the safe and stable operation of power systems.
Guangya Zhu   +5 more
doaj   +1 more source

Temporal Forward–Backward Consistency, Not Residual Error, Measures the Prediction Accuracy of Extended Dynamic Mode Decomposition

open access: yesIEEE Control Systems Letters, 2023
Extended Dynamic Mode Decomposition (EDMD) is a popular data-driven method to approximate the action of the Koopman operator on a linear function space spanned by a dictionary of functions. The accuracy of EDMD model critically depends on the quality of the particular dictionary's span, specifically on how close it is to being invariant under the ...
Masih Haseli, Jorge Cortés 0001
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy