Results 111 to 120 of about 38,007 (143)

Personalized extended interval dosing of natalizumab in MS

Neurology, 2020
To determine whether natalizumab efficacy is maintained when switching to personalized extended interval dosing based on individual natalizumab trough concentrations in patients with relapsing-remitting multiple sclerosis (RRMS).This was a prospective multicenter single-arm trial with 1 year follow-up and a 1-year extension phase.
Zoé L.E. van Kempen, Erwin L.J. Hoogervorst, Mike P. Wattjes, Nynke F. Kalkers, Jop P. Mostert, Birgit I. Lissenberg-Witte, Annick de Vries, Anja ten Brinke, Bob W. van Oosten, Frederik Barkhof, Charlotte E. Teunissen, Bernard M.J. Uitdehaag, Theo Rispens, Joep Killestein   +13 more
openaire   +3 more sources

Loading Doses and Extended Dosing Intervals in Topical Gentamicin Therapy

American Journal of Ophthalmology, 1985
Loading doses and extended dosing intervals were studied in a rabbit model using topically applied gentamicin in a concentration of 13.6 mg/ml. Loading doses consisting of one drop every minute for five minutes produced significantly higher gentamicin concentrations in the cornea during the early hours of treatment than regimens using one drop every ...
D B, Glasser, S, Gardner, J G, Ellis, T H, Pettit   +3 more
openaire   +2 more sources

Omeprazole: Extended-Interval Dosing (Alternate-Day Dosing)

Hospital Pharmacy, 2006
Off-Label Drug Uses This Hospital Pharmacy feature is extracted from Off-Label DrugFacts, a quarterly publication available from Wolters Kluwer Health. Off-Label DrugFacts is a practitioner-oriented resource for information about specific FDA-unapproved drug uses. This new guide to the literature will enable the
Joyce Generali, Dennis J. Cada
openaire   +1 more source

Lovastatin: Extended-Interval (Alternate-Day) Dosing

Hospital Pharmacy, 2001
Off-Label Drug Uses This Hospital Pharmacy feature is extracted from Off-Label DrugFacts, a quarterly publication available from Facts and Comparisons. Off-Label DrugFacts is a practitioner-oriented resource for information about specific FDA-unapproved drug uses.
Joyce Generali, Dennis J. Cada
openaire   +1 more source

Extended-interval dosing of aminoglycosides.

The Mount Sinai journal of medicine, New York, 1998
Aminoglycosides are efficacious agents. Their use has declined partly because of the development of newer, presumably less toxic agents. Research shows that aminoglycosides can be dosed differently than in the past, maintaining efficacy while reducing aminoglycoside toxicities. Aminoglycosides administered with newer agents may help overcome antibiotic
M E, Blam, G S, Hammer
openaire   +1 more source

Extended-Interval Aminoglycoside Dosing for Treatment of Enterococcal and Staphylococcal Osteomyelitis

Annals of Pharmacotherapy, 2004
BACKGROUND: Gram-positive osteomyelitis requires long-term antibiotic therapy, much of which is often administered in the outpatient setting. Historically, synergistic aminoglycoside use in these infections requires multiple daily doses, which can be inconvenient.
A Christie, Graham, Renee-Claude, Mercier, Louis E, Achusim, Manjunath P, Pai   +3 more
openaire   +2 more sources

Two nomograms for determining extended-dosing intervals for gentamicin in neonates

American Journal of Health-System Pharmacy, 2008
The development of two nomograms to predict dosing intervals for gentamicin in neonates based on one gentamicin concentration is described.Pooled data from three retrospective studies on neonates age seven days or younger were used to create nomograms that would predict dosing intervals for gentamicin.
John E, Murphy, Anthony M, Roether
openaire   +2 more sources

Extended-interval dosing of natalizumab in NOVA

The Lancet Neurology, 2023
Olaf, Stüve, Bastian, Tugemann
openaire   +2 more sources

Extended-Interval dosing of tobramycin in neonates: Implications for therapeutic drug monitoring

Clinical Pharmacology & Therapeutics, 2002
Our objective was to individualize tobramycin dosing regimens in neonates of various gestational ages with use of early therapeutic drug monitoring.This study was performed in neonatal patients with suspected septicemia in the first week of life. All patients received tobramycin, 4 mg/kg per dose, as a 30-minute intravenous infusion, with a gestational
de Hoog, Matthijs, Mouton, Johan, Schoemaker, RC, Verduin, CM, van den Anker, John   +4 more
openaire   +2 more sources

Extended interval gentamicin dosing in obstetrics

American Journal of Obstetrics and Gynecology, 2023
Li C, Hardy E, Moreno K
openaire   +1 more source