Results 231 to 240 of about 514,808 (265)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Genetic Influence on Extended-Release Naltrexone Treatment Outcomes in Patients with Opioid Use Disorder: An Exploratory Study. [PDF]

Brain Sci
Juya F, Klemmetsby Solli K, Sannes AC, Weimand B, Gjerstad J, Tanum L, Mordal J.   +6 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Evaluation of Efficacy and Review of Side Effect Profile in Epilepsy Patients Treated with Extended-Release Levetiracetam. [PDF]

Pak J Med Sci
Ozdemir Z, Cokkacar FA, Eren F, Gul G.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Medications for OUD: Extended-Release Naltrexone. [PDF]

Curr Addict Rep
Srivastava AB.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Engineering Extended Release Profiles for Biologic Formulations via Chemical Cross-Linking of Poloxamer 407 Hydrogels. [PDF]

ACS Omega
Park J, Lin YJ, Dutta K, Forster S, Okoh G, Tian Y, Liang Y.   +6 more
europepmc   +1 more source

Buprenorphine extended-release (Ethiqa XR) impacts the immunological response in mice exposed to aerosolized <i>Burkholderia pseudomallei</i> or <i>Yersinia pestis</i>. [PDF]

Front Immunol
Rodriguez CI, Klimko CP, Davies ML, Dankmeyer JL, Rill NO, Hunter M, Smith BA, Wheeler TK, Webster-Zahnow WM, Swamotz AM, Hernandez-Viezcas Y, Xander C, Martinez EE, Toothman RG, Mlynek KD, Bozue JA, Qiu J, Biryukov SS, Cote CK.   +18 more
europepmc   +1 more source