Results 1 to 10 of about 468,060 (214)
Biocomposite for Prolonged Release of Water-Soluble Drugs [PDF]
Pharmaceutics, 2023 This study aimed to develop a prolonged-release system based on palygorskite and chitosan, which are natural ingredients widely available, affordable, and accessible.
Lyghia M. A. Meirelles +6 more
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Application of Hydrophilic Polymers to the Preparation of Prolonged-Release Minitablets with Bromhexine Hydrochloride and Bisoprolol Fumarate [PDF]
PharmaceuticsMinitablets have been extensively studied in recent years as a convenient pediatric form because they allow successful administration even in very young children.
Agata Grzejdziak +5 more
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Alternative Pharmacokinetic Metrics in Single-Dose Studies to Ensure Bioequivalence of Prolonged-Release Products at Steady State—A Case Study [PDF]
Pharmaceutics, 2023 (1) Background: this article investigates which PK metrics in a single-dose study (concentration at the end of posology interval, Cτ, partial areas under the curve, pAUCs, or half-value duration, HVD) are more sensitive and less variable for predicting ...
Víctor Mangas-Sanjuán +8 more
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Targeting heterogeneous depression with trazodone prolonged release: from neuropharmacology to clinical application [PDF]
Annals of General PsychiatryAim This paper evaluates the clinical efficacy, safety, and practical implications of Trazodone Prolonged Release (PR) in managing depression, anxiety, and sleep disorders, with a focus on its multimodal mechanism of action and advantages over ...
Andrea Fagiolini +6 more
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Pharmaceutics, 2023 Solid dosage forms based on hypromellose (HPMC) with prolonged/extended drug release are very important from the research and industrial viewpoint. In the present research, the influence of selected excipients on carvedilol release performance from HPMC ...
Tadej Ojsteršek +2 more
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Неврология, нейропсихиатрия, психосоматика, 2023 The prolonged release tablets form of alimemazine is seen as a promising agent for the long-term treatment of generalized anxiety disorder (GAD).Objective: to investigate the efficacy and safety of therapy with alimemazine (Teraligen® retard, prolonged ...
Ju. E. Azimova +2 more
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Features of using prolonged-release melatonin in patients with type 2 diabetes
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Diabetes mellitus (DM) and its complications are one of the leading causes of death worldwide, with approximately 700 million people expected to suffer from DM by 2045, according to the International Diabetes Federation.
P.P. Kravchun +2 more
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Ceramics, 2022 Local drug delivery systems are an effective approach in the treatment of purulent–septic inflammation of bone tissue. Chemically bonded multiphase ceramics based on calcium-deficient carbonate-substituted hydroxyapatite combine resorbability ...
Yuliya Lukina +12 more
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Pharmaceutics, 2023 Local chemotherapy using polymer drug delivery systems has the potential to treat some cancers, including intraocular retinoblastoma, which is difficult to treat with systemically delivered drugs.
Radka Hobzova +9 more
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Orodispersible films (ODF) in individualized therapy [PDF]
Farmacja Polska, 2019 One of the mains factors affecting the effectiveness and safety of the therapy is the development of an appropriate dosage form adapted to the age of the patients and ease to administer as well as a dosing devices that provide flexible dosing.
Ewelina Łyszczarz +2 more
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