Results 1 to 10 of about 492,682 (218)

Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets

open access: yesAsian Journal of Pharmaceutical Sciences, 2019
The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques.
Hui Xu   +5 more
doaj   +3 more sources

Long-Acting Opioid Analgesics for Acute Pain: Pharmacokinetic Evidence Reviewed

open access: yesVeterinary Sciences, 2023
Long-acting injectable (LAI) opioid formulations mitigate the harm profiles and management challenges associated with providing effective analgesia for animals. A single dose of a long-acting opioid analgesic can provide up to 72 h of clinically relevant
Betty M. Tyler, Michael Guarnieri
doaj   +1 more source

Solvent-Free Polycaprolactone Dissolving Microneedles Generated via the Thermal Melting Method for the Sustained Release of Capsaicin

open access: yesMicromachines, 2021
(1) Background: Dissolving microneedles (DMNs), a transdermal drug delivery system, have been developed to treat various diseases in a minimally invasive, painless manner.
Jaehong Eum   +5 more
doaj   +1 more source

Efficacy, Safety, and Retention Rate of Extended-Release Divalproex Versus Conventional Delayed-Release Divalproex: A Meta-Analysis of Controlled Clinical Trials

open access: yesFrontiers in Pharmacology, 2022
Purpose: A novel once-daily divalproex-extended release (ER) dose formulation has been developed; this formulation prolongs the therapeutic serum levels of the drug, compared with the twice-daily conventional divalproex-delayed release (DR) formulation ...
Chen Qi Zhang   +6 more
doaj   +1 more source

Comparative Study of Selected Excipients’ Influence on Carvedilol Release from Hypromellose Matrix Tablets

open access: yesPharmaceutics, 2023
Solid dosage forms based on hypromellose (HPMC) with prolonged/extended drug release are very important from the research and industrial viewpoint. In the present research, the influence of selected excipients on carvedilol release performance from HPMC ...
Tadej Ojsteršek   +2 more
doaj   +1 more source

A Novel Polymer Insect Repellent Conjugate for Extended Release and Decreased Skin Permeation of Para-Menthane-3,8-Diol

open access: yesPharmaceutics, 2021
Background: We developed a novel polymer insect repellent conjugate for extended release and decreased skin permeation of the volatile insect repellent p-menthane-3,8-diol (PMD).
Sayyed I. Shah   +2 more
doaj   +1 more source

Treatment-Continuity of ADHD Compared Using Immediate-Release and Extended-Release MPH

open access: yesPediatric Neurology Briefs, 2005
The continuity of methylphenidate (MPH) therapy for ADHD in young Medicaid beneficiaries (ages 6 to 17 years) treated with immediate-release (IR) or extended-release (ER) MPH formulations was compared in an analysis of statewide California Medicaid ...
J Gordon Millichap
doaj   +1 more source

Formulation and Evaluation of Xanthan Gum Microspheres for the Sustained Release of Metformin Hydrochloride

open access: yesMicromachines, 2023
This work aimed to formulate xanthan gum microspheres for the encapsulation of metformin hydrochloride, according to the process of ionotropic gelation. The obtained microparticles, based on various fractions of xanthan gum (0.5–1.25), were subjected to ...
Madiha Melha Yahoum   +8 more
doaj   +1 more source

Thermal latency studies in opiate-treated mice

open access: yesJournal of Pharmacy and Bioallied Sciences, 2014
Background: The change in the reaction time of a tail or paw exposed to a thermal stimulus is a measure of nociceptive activity in laboratory animals. Tail-flick and plantar thermal sensitivity (Hargreaves) tests are non-invasive, minimize stress, and ...
Noam Schildhaus   +7 more
doaj   +1 more source

Influence of Splitting on Dissolution Properties of Metoprolol Tablets

open access: yesBiomolecules & Biomedicine, 2009
The objective of this work was to compare several profiles of dissolution data for metoprolol controlled release tablet formulations in order to identify possible changes in dissolution profiles of whole and scored tablets.
Edina Vranić, Alija Uzunović
doaj   +1 more source

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