Results 31 to 40 of about 514,808 (265)

The Effect of Once-Daily Gabapentin Extended Release Formulation in Patients With Postamputation Pain

Frontiers in Pharmacology, 2019
ObjectivesTo compare gabapentin extended-release, a gastro-retentive formulation, in relieving postamputation pain among gabapentin-experienced and gabapentin-naïve patients.DesignOpen-labeled pilot study.SubjectsSixteen patients with postamputation pain
Nebojsa Nick Knezevic, Nebojsa Nick Knezevic, Nebojsa Nick Knezevic, Tabish Aijaz, Kenneth D. Candido, Kenneth D. Candido, Kenneth D. Candido, Svetlana Kovaleva, Alexei Lissounov, Ivana Knezevic   +9 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Preparation and characterization of a coacervate extended-release microparticulate delivery system for Lactobacillus rhamnosus

, 2011
Sk Md Athar Alli Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, IndiaBackground: The purpose of this study was to develop a mucoadhesive coacervate microparticulate system to deliver viable Lactobacillus rhamnosus ...
Mohammed Athar Alli Sheikh, Alli SMA
core   +1 more source

Bioavailability Enhancement of Curcumin by PEG-Based Gastroretentive System: Development and In Vitro Evaluation

Pharmaceutics
Background/Objectives: Increasing the bioavailability of poorly absorbed drugs is a continuous challenge in modern pharmaceutical technology. This is due to the problematic nature of BCS class IV active pharmaceutical ingredients: these drugs possess ...
Orsolya Csendes, Gábor Vasvári, Ádám Haimhoffer, László Horváth, Monika Béresová, Attila Bényei, Ildikó Bácskay, Pálma Fehér, Zoltán Ujhelyi, Dániel Nemes   +9 more
doaj   +1 more source

Optimization and modeling of PEGylated, hydrocortisone‐17‐butryate‐loaded poly(lactic‐co‐glycolic acid) microspheres

Nano Select, 2023
We propose by surface functionalizing poly(lactic‐co‐glycolic acid) (PLGA) microspheres we can increase bioavailability and therapeutic duration of hydrocortisone‐17‐butyrate delivery for an intra‐articular injection.
Nathaniel M. Myers, Noelle K. Comolli
doaj   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Bioequivalence of oxymorphone extended release and crush-resistant oxymorphone extended release

Drug Design, Development and Therapy, 2011
Irma H Benedek, Janet Jobes, Qinfang Xiang, William D Fiske Endo Pharmaceuticals Inc, Chadds Ford, PA, USA Background: A formulation of crush-resistant extended-release opioids may deter abuse. The purpose of this study was to evaluate the bioequivalence
Fiske WD, Xiang Q, Jobes J, Benedek IH
doaj  

Influence of Topically Applied Menthol Gel Formulation on Cooling Efficacy and Sustained Release: A FLIR Thermography and Franz Diffusion Study

International Journal of Pain
Background : Cryotherapy literally means that cold therapy; cold can also reduce swelling and inflammation. Cold therapy is an ancient remedy for the pain management, when an injury or inflammation, such as tendonitis or bursitis occurs, tissues are ...
Lopamudra Mohanty, Ekta Yadav, Jayaganesh Sankar, Punita Kalra   +3 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Extended-release tofacitinib for refractory Behçet disease

Medicine, 2022
. Rationale:. Although single-cytokine inhibitors can be considered in treating severe or refractory Behçet disease (BD), these biologic agents are associated with potential therapeutic failure due to the multi-cytokine pathogenesis involving Th1- and ...
Chrong-Reen Wang, MD, PhD, Tak-Wah Wong, MD, PhD, Sheng-Min Hsu, MD, PhD, Maya Saranathan.   +3 more
doaj   +1 more source