Hydrogel Vehicles for Enteric-Coated Pantoprazole Minitablets: Impact of Polymer Type on Rheology and Drug Release [PDF]
GelsThe development of age-appropriate pediatric dosage forms remains an important challenge, particularly for acid-labile drugs requiring gastro-resistant protection.
Maja Frankiewicz +9 more
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Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets [PDF]
PharmaceuticsBackground/Objectives: This study investigated how selected functionality-related characteristics (FRCs) of hypromellose (HPMC)—namely viscosity, hydroxypropoxy substitution, particle size, and the ratio of water-soluble (FlowLac® 100) to water-insoluble
Tadej Ojsteršek +2 more
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Hydroxypropyl Methylcellulose—A Key Excipient in Pharmaceutical Drug Delivery Systems [PDF]
PharmaceuticsHydroxypropyl methylcellulose (Hypromellose, HPMC) is a well-known excipient used in the pharmaceutical and nutraceutical fields due to its versatile physicochemical properties.
Robert-Alexandru Vlad +6 more
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Hypromellose-, Gelatin- and Gellan Gum-Based Gel Films with Chlorhexidine for Potential Application in Oral Inflammatory Diseases [PDF]
GelsThe oral cavity is constantly exposed to contact with an external environment. Pathogens can easily access and colonize it, causing a number of medical conditions that are usually accompanied by inflammation, which in turn require medical intervention ...
Monika Wojtyłko +2 more
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Interactions Between Paracetamol and Hypromellose in the Solid State
Frontiers in Pharmacology, 2019 Hydroxypropyl methylcellulose (hypromellose) is a widely known excipient commonly used in the preparation of drug formulations. It can interact with some active pharmaceutical ingredients (APIs), thereby contributing to a reduction in crystallinity ...
Edyta Leyk +2 more
exaly +3 more sources
Hydroxypropyl Methylcellulose Capsules Enhance Aerodynamic Performance of Carrier-Based Dry Powder Inhaler Formulations: A Comprehensive Evaluation of Capsule Material Effects [PDF]
PharmaceuticsBackground/Objectives: This study aims to investigate the underexplored impact of capsule type on the performances of capsule-based dry powder inhalers (cDPIs).
Camille Dumont +8 more
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Регуляторные исследования и экспертиза лекарственных средств, 2023 Scientific relevance. Hypromellose phthalate is used in enteric coatings for oral medicinal products. The proportion of phthalate groups in the polymer is standardised because it has a significant effect on solubility.
S. V. Moiseev +4 more
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Регуляторные исследования и экспертиза лекарственных средств, 2023 Scientific relevance. Hypromellose phthalate is a component of enteric coatings used to modify active substance release from oral medicinal products in the small intestine.
N. E. Kuz’mina +4 more
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Hypromellose improves mydriasis dynamics by phenylephrine in a rabbit experimental model
Российский офтальмологический журнал, 2023 Purpose: to determine the main characteristics of the mydriatic effect of drug formulations of phenylephrine, containing and not containing hypromellose, hyaluronic acid as an auxiliary component, in a comparative in vivo study, as well as to study their
E. V. Blinova +7 more
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Oftalʹmologiâ, 2023 Dosage forms for topical ocular administration are the basis of patient management in ophthalmology. The eye is a structure evolutionarily protected from the effects of xenobiotics by a number of physiological and anatomical barriers.
O. I. Butranova, S. K. Zyryanov
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