Results 21 to 30 of about 3,320 (170)

Effects of the Topical Use of the Natural Antioxidant Alpha-Lipoic Acid on the Ocular Surface of Diabetic Patients with Dry Eye Symptoms

Frontiers in Bioscience-Landmark, 2022
Purpose: The purpose of this study is to investigate the effects of the treatment with eye-drops based on a combination of antioxidant and mucomimetic molecules, namely 0.1% alpha-lipoic acid (ALA) and 0.3% hydroxy-propyl-methylcellulose (HPMC) on the ...
Anna M. Roszkowska, Rosaria Spinella, Giovanni W. Oliverio, Elisa I. Postorino, Giuseppe A. Signorino, Dario Rusciano, Pasquale Aragona   +6 more
doaj   +1 more source

Imaging of the Effect of Alcohol-Containing Media on the Performance of Hypromellose Hydrophilic Matrix Tablets: Comparison of Direct Compression and Regular Grades of Polymer

Pharmaceutics, 2020
As the ingestion of drug products with alcohol could have adverse effects on the release of drugs from dosage forms, it is important to understand the mechanisms underpinning the influence on drug release by evaluating the effect of alcohol-containing ...
Nihad Mawla, Sarah Hanley, Karl Walton, Waseem Kaialy, Tariq Hussain, Adam Ward, Jonathan Brown, Barbara R. Conway, Peter Timmins, Kofi Asare-Addo   +9 more
doaj   +1 more source

Use of Eco-friendly recipients for vitrification of Hyphessobrycon boulengery Spermatogonial cells [PDF]

Anais da Academia Brasileira de Ciências
The aim of the study was to evaluate the efficiency of the gelatin and Hypromellose capsules as recipients to vitrification of lambari spermatogonial cells. In experiment 1, four protocols to vitrification (P1, P2, P3 and P4) were tested. The protocol P3
KAREL GELINA TORRES-LOZANO, THAIZA R. DE FREITAS, RÔMULO B. RODRIGUES, FRANCIELLI W.S. CIBIN, CLARA C. SILVA, EDUARDO THOMÉ NICOLETI, RENATA V. DANTAS, DOUGLAS C. SELLE, DARCI C. FORNARI, DANILO PEDRO STREIT JUNIOR   +9 more
doaj   +1 more source

Application of Focus Variation Microscopy and Dissolution Imaging in Understanding the Behaviour of Hydrophilic Matrices

Pharmaceutics, 2020
Hydrophilic matrix systems can be found in a wide range of extended release pharmaceutical formulations. The main principle of these systems is that upon contact with water, the hydrophilic component swells to form a hydrated gel layer which controls ...
Adam Ward, Benedict Brown, Karl Walton, Peter Timmins, Barbara R. Conway, Kofi Asare-Addo   +5 more
doaj   +1 more source

A Dry Powder Platform for Nose-to-Brain Delivery of Dexamethasone: Formulation Development and Nasal Deposition Studies

Pharmaceutics, 2021
Nasal route of administration offers a unique opportunity of brain targeted drug delivery via olfactory and trigeminal pathway, providing effective CNS concentrations at lower doses and lower risk for adverse reactions compared to systemic drug ...
Laura Nižić Nodilo, Ivo Ugrina, Drago Špoljarić, Daniela Amidžić Klarić, Cvijeta Jakobušić Brala, Mirna Perkušić, Ivan Pepić, Jasmina Lovrić, Vesna Saršon, Maša Safundžić Kučuk, Dijana Zadravec, Livije Kalogjera, Anita Hafner   +12 more
doaj   +1 more source

Transdermal Patches for Delivery of Beta-Blockers

European Pharmaceutical Journal, 2021
Transdermal matrices containing 1.258 mg/cm2 of propranolol and consisting of ethylcellulose (EC), castor oil, and hydroxypropylmethylcellulose (HPMC) or halloysite (HA) were prepared.
Rohaľová S., Guman M., Wolaschka T.
doaj   +1 more source

The Impact of Hypromellose on Pharmaceutical Properties of Alginate Microparticles as Novel Drug Carriers for Posaconazole

, 2023
Fungal infections are a group of diseases which are challenging to treat because of drug-resistant fungi species, drug toxicity, and often severe patient conditions. Hence, research into new treatments, including new therapeutic substances and novel drug
Katarzyna Winnicka, Katarzyna Kruk, Marta Szekalska, Anna Basa   +3 more
core   +1 more source

Comparative Evaluation of the Powder and Tableting Properties of Regular and Direct Compression Hypromellose from Different Vendors

Pharmaceutics, 2023
Hypromellose, a widely used polymer in the pharmaceutical industry, is available in several grades, depending on the percentage of substitution of the methoxyl and hydroxypropyl groups and molecular weight, and in various functional forms (e.g., suitable
Nihad Mawla, Maen Alshafiee, John Gamble, Mike Tobyn, Lande Liu, Karl Walton, Barbara R. Conway, Peter Timmins, Kofi Asare-Addo   +8 more
doaj   +1 more source

Dynamic mechanical thermal analysis of hypromellose 2910 free films [PDF]

, 2011
It is common practice to coat oral solid dosage forms with polymeric materials for controlled release purposes or for practical and aesthetic reasons. Good knowledge of thermo-mechanical film properties or their variation as a function of polymer grade ...
CASETTARI, LUCA, BONACUCINA, Giulia, Giovanna Mencarelli, G. Bonacucina, G. F. Palmieri, Marco Cespi, Giovanni Filippo Palmieri, G. Mencarelli, Giulia Bonacucina, Luca Casettari, L. Casettari, PALMIERI, Giovanni Filippo, M. Cespi, CESPI, MARCO   +13 more
core   +1 more source

Development of a novel method utilising dissolution imaging for the measurement of swelling behaviour in hydrophilic matrices

International Journal of Pharmaceutics: X, 2019
A variety of imaging techniques are currently used within the field of pharmaceutics to help understand and determine a wide range of phenomena associated with drug release from hydrophilic matrix tablets.
Adam Ward, Karl Walton, Nihad Mawla, Waseem Kaialy, Lande Liu, Peter Timmins, Barbara R. Conway, Kofi Asare-Addo   +7 more
doaj   +1 more source