Results 101 to 110 of about 1,597 (254)

Anti-Disturbance for ST-VTOL UAV via Sliding Mode Control with Enhanced Observer

Drones
As a classical disturbance observation method, the extended state observer (ESO) is commonly used in controllers for disturbance estimation and feedback control.
Jiahui Zhang, Jinwu Xiang, Daochun Li, Gang Yang, Weicheng Di, Ligang Zhang, Zhan Tu   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An integrated solution for 3D overhead cranes: Time-optimal motion planning, obstacle avoidance, and anti-swing

Engineering Science and Technology, an International Journal
This paper proposed a motion planning scheme, a nonlinear controller integrated with an observer for a three-dimensional overhead crane (3DOC) nonlinear system.
Van Chung Nguyen, Hue Luu Thi, Hoa Bui Thi Khanh, Huy Nguyen Danh, Dai Pham Duc, Tung Lam Nguyen   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Improved sliding mode path tracking control for automated guided vehicles with the disturbances compensation

International Journal of Advanced Robotic Systems
This article investigates the path tracking problem for the two-wheel differential drive automated guided vehicles (AGVs) under the influence of unknown disturbances. Firstly, a state observer and a radial basis function (RBF) neural network are combined
Jun Nie, Xinyu Zhang, Chunyang Sheng, Haixia Wang, Xiao Lu   +4 more
doaj   +1 more source

Experimental Verifications of Vibration Suppression for a Smart Cantilever Beam with a Modified Velocity Feedback Controller

Shock and Vibration, 2014
This paper presents various experimental verifications for the theoretical analysis results of vibration suppression to a smart flexible beam bonded with a piezoelectric actuator by a velocity feedback controller and an extended state observer (ESO ...
Ting Zhang, Hong Guang Li, Guo Ping Cai, Fu Cai Li   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source