Results 51 to 60 of about 19,987 (262)

Serious Gaming Technology in Upper Extremity Rehabilitation: Scoping Review

open access: yesJMIR Serious Games, 2020
BackgroundSerious gaming has increasingly gained attention as a potential new component in clinical practice. Specifically, its use in the rehabilitation of motor dysfunctions has been intensively researched during the past three decades ...
Koutsiana, Elisavet   +5 more
doaj   +1 more source

Normal Form Structures in Extensive Form Games [PDF]

open access: yesJournal of Economic Theory, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mailath, George J.   +2 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

extensive form games

open access: yes, 1983
The most general model used to describe conflict situations is the extensive form model, which specifies in detail the dynamic evolution of each situation and thus provides an exact description of ‘who knows what when’ and ‘what is the consequence of which’.
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

“MILITANCY” CONCEPT-SPHERE’S SEMIOLINGUISTIC ACTUALIZATION IN ADVERTISING DISCOURSE

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2020
The paper focuses on the clusters of signs that support semiosis of belligerency and contribute to actualization of the concept-sphere “Militancy” in creolized advertising texts.
Daria G. Kurenova, Andrey V. Olyanich
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A Method for Distributed Control of Reactive Power and Voltage in a Power Grid: A Game-Theoretic Approach

open access: yesEnergies, 2018
The efficiency of a power system is reduced when voltage drops and losses occur along the distribution lines. While the voltage profile across the system buses can be improved by the injection of reactive power, increased line flows and line losses could
Ikponmwosa Idehen   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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