Results 61 to 70 of about 1,620,578 (347)

The SLS-Berlin: Validation of a German Computer-Based Screening Test to Measure Reading Proficiency in Early and Late Adulthood [PDF]

open access: yes, 2019
Reading proficiency, i.e., successfully integrating early word-based information and utilizing this information in later processes of sentence and text comprehension, and its assessment is subject to extensive research.
Froehlich, Eva   +3 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

An Analysis of Reading Performances of Indonesian EFL Learners for Extensive Reading Practice [PDF]

open access: yes, 2017
Learners\u27 reading performances are needed to be studied in order to clarify the appropriate context of studies about learners\u27 extensive reading experiences.
Delfi, S. (Syofia), Yamat, H. (Hamidah)
core   +1 more source

Simple and Effective Curriculum Pointer-Generator Networks for Reading Comprehension over Long Narratives

open access: yes, 2019
This paper tackles the problem of reading comprehension over long narratives where documents easily span over thousands of tokens. We propose a curriculum learning (CL) based Pointer-Generator framework for reading/sampling over large documents, enabling
Fu, Jie   +8 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Extensive Reading (ER) Practices and the Development of Language Fluency

open access: yesLingua Cultura, 2018
This research aimed at investigating the Extensive Reading (ER) practices of the students and the development of language fluency. The design of the research was a qualitative study using purposive sampling technique.
Resky - Januarty
doaj   +3 more sources

Intensive reading and extensive reading in teaching reading comprehension [PDF]

open access: yesLingua Pedagogia, Journal of English Teaching Studies, 2020
The research investigated the implementation of Intensive Reading (IR) and Extensive Reading (ER) that is suitable for English class in Polytechnic that focuses on the ability of English practice. This research is a Classroom Action Research (CAR), which consists of three stages, namely pretest, treatment, and posttest.
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

EXPECTATIONS AND EXPERIENCES OF INDONESIAN TEACHERS WHO HAVE, AND HAVE NOT, DONE EXTENSIVE READING

open access: yesTEFLIN Journal, 2019
Extensive Reading (ER) in Indonesia is in its infancy. Over the past 2-3 years a small band of ER enthusiasts led by the Indonesian Extensive Reading Association (IERA) and the Extensive Reading Foundation (ERF) have started promoting ER in the ...
Rob Waring, Nida Husna
doaj   +1 more source

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