Extensively Drug-Resistant Mycobacterium tuberculosis, India
To the Editor: India is contributing nearly one third of the world’s tuberculosis (TB) cases and has the highest rate of new TB cases (1). Prevalence of multidrug-resistant TB (MDR TB) cases is on the rise in India, and proportions of new cases of MDR TB have been observed to vary from 1.1% to 5.3% in most of the reported studies.
Rajesh Mondal, Amita Jain
doaj +3 more sources
Extensively drug-resistant tuberculosis: epidemiology and management
Alberto Matteelli,1 Alberto Roggi,1 Anna CC Carvalho21Institute of Infectious and Tropical Diseases, WHO Collaborating Centre for TB/HIV Co-Infection, University of Brescia, Brescia, Italy; 2Laboratory of Innovations in Therapies, Education and ...
Matteelli A, Roggi A, Carvalho ACC
doaj +6 more sources
Extensively Drug-resistant Tuberculosis, Italy and Germany
To the Editor: Twenty-three countries have reported >1 case of extensively drug-resistant tuberculosis (XDR TB) (1); however, information about XDR TB is still incomplete. In particular, the response of XDR TB to treatment in countries with low incidence is not known. We compared mortality rates from XDR TB with those from multidrug-resistant (MDR) TB.
Giovannittista Migliori +9 more
doaj +3 more sources
Multidrug- and Extensively Drug-Resistant Tuberculosis, Germany
We evaluated risk factors and treatment outcomes associated with multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) in Germany in 2004–2006. In 177 (4%) of 4,557 culture-positive TB cases, Mycobacterium tuberculosis isolates
Barbara Eker +10 more
doaj +3 more sources
Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa.
N. Sarita Shah +11 more
doaj +3 more sources
Comprehensive Treatment of Extensively Drug-Resistant Tuberculosis [PDF]
Extensively drug-resistant tuberculosis has been reported in 45 countries, including countries with limited resources and a high burden of tuberculosis. We describe the management of extensively drug-resistant tuberculosis and treatment outcomes among patients who were referred for individualized outpatient therapy in Peru.A total of 810 patients were ...
Mitnick, Carole D. +26 more
openaire +5 more sources
Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]
Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill +48 more
core +21 more sources
XDR-TB, extensively drug-resistant tuberculosis
Ernesto Jaramillo
doaj +5 more sources
[Extensively drug-resistant tuberculosis treated with bedaquiline]. [PDF]
López Pérez A +4 more
europepmc +3 more sources
Extensively drug-resistant tuberculosis [PDF]
To describe the origin, epidemiology, diagnosis, treatment, prevention, and control of extensively drug-resistant tuberculosis (XDR TB).XDR TB is defined as the occurrence of TB in persons whose Mycobacterium tuberculosis isolates are resistant to isoniazid and rifampin and to any fluoroquinolone and at least one of three injectable second-line drugs ...
Mandeep, Jassal, William R, Bishai
openaire +4 more sources

