Results 81 to 90 of about 3,057,829 (262)

Low-cost rapid detection of rifampicin resistant tuberculosis using bacteriophage in Kampala, Uganda. [PDF]

open access: yes, 2007
BACKGROUND: Resistance to anti-tuberculosis drugs is a serious public health problem. Multi-drug resistant tuberculosis (MDR-TB), defined as resistance to at least rifampicin and isoniazid, has been reported in all regions of the world.
Traore, Hamidou   +38 more
core   +1 more source

Capacity building in medicines development and regulation in Africa—Overview on recent progress

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke   +7 more
wiley   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Outbreak Caused by Multidrug-Resistant Mycobacterium Tuberculosis with Unusual Combination of Resistance Mutations, Northern Argentina, 2006–2022

open access: yesEmerging Infectious Diseases
To reconstruct transmission chains of the multidrug-resistant tuberculosis Ch strain, which harbors a unique combination of resistance mutations, we analyzed genomes of 25 isolates from 12 patients with diagnosis during 2006–2022 in Chaco Province ...
Roxana Paul   +13 more
doaj   +1 more source

Molecular epidemiology of tuberculosis in selected sites across Papua New Guinea [PDF]

open access: yes, 2014
With an estimated one third of the global population being infected with latent tuberculosis (TB) and 8.6 million people developing active TB in 2012, this infectious disease remains a major global health concern.
Ley, Serej Delphine
core   +1 more source

Carrion ecology: concepts, interdisciplinary synthesis, and perspectives

open access: yesBiological Reviews, EarlyView.
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón   +38 more
wiley   +1 more source

Resistance patterns and trends of extensively drug-resistant tuberculosis: 5-year experience [PDF]

open access: yesJournal of Microbiology and Infectious Diseases, 2013
Objective:Extensively drug-resistant tuberculosis (XDR-TB) strains were emerged when multidrug-resistant TB (MDR- TB) was inadequately treated. Inadequate treatment of MDR-TB cases may result in additional resistance especially non-XDR-TB and then XDR ...
Amresh Kumar Singh   +6 more
doaj   +1 more source

Resistance to Second-Line Anti-TB Drugs in Cambodia: A Phenotypic and Genetic Study

open access: yesInfection and Drug Resistance, 2021
Sokleaph Cheng,1– 3 Mallorie Hide,3– 5 Sok Heng Pheng,6 Alexandra Kerléguer,2 Gauthier Delvallez,2 Sophan Sam,7 Tan Eang Mao,6 Thi Van Anh Nguyen,3,8 Anne-Laure Bañuls3– 5 1Institut Pasteur du Cambodge and Ministry of ...
Cheng S   +8 more
doaj  

Challenges and Controversies in Defining Totally Drug-Resistant Tuberculosis

open access: yesEmerging Infectious Diseases, 2012
In March 2012, in response to reports of tuberculosis (TB) resistant to all anti-TB drugs, the World Health Organization convened an expert consultation that identified issues to be resolved before defining a new category of highly drug-resistant TB ...
Peter Cegielski   +8 more
doaj   +1 more source

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