Results 91 to 100 of about 3,057,829 (262)

Treatment of drug-resistant tuberculosis

, 2011
Lancelot Pinto1,2, Dick Menzies1,21Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, QC, Canada; 2Department of Epidemiology and Biostatistics, McGill University, Montreal, QC, CanadaClinical question: What is the ...
Dick Menzies, Pinto LM, Menzies D
core   +1 more source

Primary Antimicrobial Resistance Among Mycobacterium Tuberculosis Isolates from HIV Seropositive and HIV Seronegative Patients in Dar es Salaam Tanzania. [PDF]

, 2008
The United Republic of Tanzania is one of the 22 high M. tuberculosis burden countries. Data collected between 2002 and 2007 indicate that the global prevalence of drug-resistant M. tuberculosis including MDR vary greatly.
Saathoff, Elmar, Mugusi, F., Saathoff, E., Moshiro Candida, Bosch, R., Urassa, W., Urassa, Willy, Mugusi Ferdinand, Fawzi Wafaie, Villamor, E., Mugusi, Ferdinand, Moshiro, C., Fawzi, W., Bosch, Ronald, Saathoff Elmar, Bosch Ronald, Msamanga Gernard, Msamanga, Gernard, Moshiro, Candida, Villamor Eduardo, Villamor, Eduardo, Fawzi, Wafaie, Urassa Willy   +22 more
core   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source

Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM) : study protocol for a randomized controlled trial [PDF]

, 2014
Background In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated ...
Squire, Stephen Bertel, Squire, S Bertel, Patrick PJ Phillips, Madan, Jason, Rusen, I. D., Chiang, Chen-Yuan, Armand Van Deun, Chiang, Chen Yuan, Gabriela Torrea, Phillips, P. (Patrick), Van Deun, Armand, Rusen, ID, Meredith, Sarah K, Jason Madan, Meredith, Sarah K., Nunn, Andrew J, ID Rusen, Nunn, Andrew J., Squire, Bertie, Torrea, Gabriela, Chen-Yuan Chiang, Sarah K Meredith, Phillips, Patrick PJ, Andrew J Nunn, Phillips, Patrick P.J., S Bertel Squire   +25 more
core   +2 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia

Emerging Infectious Diseases, 2017
Although pyrazinamide is commonly used for tuberculosis treatment, drug-susceptibility testing is not routinely available. We found polymorphisms in the pncA gene for 70% of multidrug-resistant and 96% of extensively drug-resistant Mycobacterium ...
Salim Allana, Elena Shashkina, Barun Mathema, Nino Bablishvili, Nestani Tukvadze, N. Sarita Shah, Russell R. Kempker, Henry M. Blumberg, Pravi Moodley, Koleka Mlisana, James C.M. Brust, Neel R. Gandhi   +11 more
doaj   +1 more source

The timing of death in patients with tuberculosis who die during anti-tuberculosis treatment in Andhra Pradesh, South India [PDF]

, 2011
Background: India has 2.0 million estimated tuberculosis (TB) cases per annum with an estimated 280,000 TBrelated deaths per year. Understanding when in the course of TB treatment patients die is important for determining the type of intervention to be ...
Tetali, S, Harries Anthony D, Rao Srinivas, Jonnalagada, Subbanna, Kannuri, Nanda K, Peri, Sundaresh, Kannuri, N K, Srinath Satyanarayana, Peri, S, Peri Sundaresh, Harries, Anthony D, Anchala, Raghupathy, Zachariah Rony, Anchala Raghupathy, Ranganadha Rao, Jonnalagada, S, Rao Ranganadha, Rao, Ranganadha, Jonnalagada Subbanna, Nanda K Kannuri, Zachariah, Rony, Rao, Srinivas, Harries, A D, Rao, S, Shailaja Tetali, Rao, R, Satyanarayana Srinath, Tetali Shailaja, Anthony D Harries, Satyanarayana, Srinath, Zachariah, R, Tetali, Shailaja, Anchala, R, Kannuri Nanda K, Satyanarayana, S, Keshav Chander, G, G Keshav Chander, Keshav Chander G, Sundaresh Peri, Raghupathy Anchala, Subbanna Jonnalagada, Rony Zachariah, Srinivas Rao   +42 more
core   +2 more sources

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

The role of the Interferon gamma release assay in assessing recent tuberculosis transmission in a hospital incident [PDF]

, 2011
In 2007, an extensive contact screening investigation into onward transmission of tuberculosis was instigated at a hospital in Northern Ireland following diagnosis of pulmonary multi-drug resistant TB in a healthcare worker.
Abubakar, Ibrahim, Nikolayevskyy, V, Elizabeth Davies, Abubakar, I, Flanagan, P, Paul Kelly, Davies Elizabeth, Abubakar Ibrahim, O'Connor, K, Vladislav Nikolayevskyy, Davies, E, Nikolayevskyy Vladislav, Bradshaw Louise, Flanagan, Peter, Davies, Elizabeth, Devine, M, Devine, Michael, Kevin O'Connor, Peter Flanagan, Drobniewski, F, Kelly Paul, Nikolayevskyy, Vladislav, Drobniewski, Francis, Ibrahim Abubakar, O'Connor Kevin, O'Connor, Kevin, Louise Bradshaw, Francis Drobniewski, Bradshaw, L, Bradshaw, Louise, Kelly, Paul, Michael Devine, Flanagan Peter, Devine Michael, Kelly, P, Drobniewski Francis   +35 more
core   +2 more sources