Results 11 to 20 of about 13,315 (175)

Emergence of an extensively drug-resistant (XDR) Streptococcus pneumoniae serotype 15A by capsular switching

International Journal of Medical Microbiology, 2018
Recently, we have identified an extensively drug-resistant (XDR) Streptococcus pneumoniae serotype 15A isolate from a patient with bacterial meningitis. It belonged to sequence type 8279 (ST8279), a clone identified as XDR serotype 11A isolated in South Korea. We obtained and compared the genome sequences of an XDR 15A and an XDR 11A isolate.
Jae-Hoon Song, Doo Ryeon Chung, Kwan Soo Ko   +2 more
exaly   +3 more sources

Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017

Emerging Infectious Diseases, 2021
Multidrug-resistant tuberculosis (MDR TB), pre-extensively drug-resistant tuberculosis (pre-XDR TB), and extensively drug-resistant tuberculosis (XDR TB) complicate disease control.
Ditthawat Nonghanphithak, Angkana Chaiprasert, Saijai Smithtikarn, Phalin Kamolwat, Petchawan Pungrassami, Virasakdi Chongsuvivatwong, Surakameth Mahasirimongkol, Wipa Reechaipichitkul, Chaniya Leepiyasakulchai, Jody E. Phelan, David Blair, Taane G. Clark, Kiatichai Faksri   +12 more
doaj   +1 more source

Frequency of first and second-line drug resistance-associated mutations among resistant Mycobacterium tuberculosis clinical isolates from São Paulo, Brazil [PDF]

Memorias do Instituto Oswaldo Cruz, 2020
BACKGROUND Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the number of new cases of multidrug resistant TB (MDR-TB), pre extensively drug-resistant TB (pre-XDR-TB) and extensively drug-resistant TB ...
Tania Matsui, Juliana Maíra Watanabe Pinhata, Michelle Christiane da Silva Rabello, Angela Pires Brandão, Lucilaine Ferrazoli, Sylvia Cardoso Leão, Cristina Viana-Niero, Rosangela Siqueira de Oliveira   +7 more
doaj   +1 more source

In Vitro Activity of Cefiderocol against Extensively Drug-Resistant Pseudomonas aeruginosa: CANWARD, 2007 to 2019

Microbiology Spectrum, 2022
Cefiderocol was evaluated by broth microdilution versus 1,050 highly antimicrobial-resistant Pseudomonas aeruginosa clinical isolates from the CANWARD study (2007 to 2019).
James A. Karlowsky, Andrew J. Walkty, Melanie R. Baxter, Heather J. Adam, Philippe R. S. Lagacé-Wiens, Frank Schweizer, Denice Bay, Joseph P. Lynch, Michael R. Mulvey, George G. Zhanel   +9 more
doaj   +1 more source

Metabolomic analysis of Mycobacterium tuberculosis reveals metabolic profiles for identification of drug-resistant tuberculosis

Scientific Reports, 2023
The detection of pre-extensively (pre-XDR) and extensively drug-resistant tuberculosis (XDR-TB) is challenging. Drug-susceptibility tests for some anti-TB drugs, especially ethambutol (ETH) and ethionamide (ETO), are problematic due to overlapping ...
Pratchakan Chaiyachat, Benjawan Kaewseekhao, Angkana Chaiprasert, Phalin Kamolwat, Ditthawat Nonghanphithak, Jutarop Phetcharaburanin, Auttawit Sirichoat, Rick Twee-Hee Ong, Kiatichai Faksri   +8 more
doaj   +1 more source

Early access to bedaquiline for extensively drug-resistant (XDR) and pre-XDR tuberculosis [PDF]

European Respiratory Journal, 2019
This letter presents final safety and efficacy data from an early-access study of bedaquiline for treating (pre-)XDR-TBhttp://bit.ly ...
Irina Vasilyeva, Andrei Mariandyshev, Boris Kazennyy, Edita Davidavičienė, Nacer Lounis, Sofia Keim   +5 more
openaire   +1 more source

gene mutations in rifampin-resistant isolates from rural areas of Zhejiang, China

Journal of International Medical Research, 2021
Objective The aim was to analyze genetic mutations in the rpoB gene of rifampin-resistant Mycobacterium tuberculosis isolates (RIF R -MTB) from Zhejiang, China.
Mei-Chun Zeng, Qing-Jun Jia, Lei-Ming Tang   +2 more
doaj   +1 more source

A five-year review of prevalence and treatment outcomes of pre-extensively drug-resistant plus additional drug-resistant tuberculosis in the Henan Provincial Tuberculosis Clinical Medicine Research Centre

Journal of Global Antimicrobial Resistance, 2022
: Objectives: This study investigated the prevalence and significant clinical outcomes of pre-extensively drug-resistant plus additional drug-resistant tuberculosis (pre-XDR-plus) in Henan Provincial Chest Hospital between 2017 and 2021.
Zheng Li, Fuyong Liu, Huihui Chen, Yungang Han, Yonghe You, Yongsheng Xie, Yue Zhao, Jiao Tan, Xu Guo, Yuntao Cheng, Yali Wang, Jing Li, Meijin Cheng, Shuang Xia, Xiaodong Niu, Lukuan Wei, Wei Wang   +16 more
doaj   +1 more source

Prevalence of Extensively Drug-Resistant Tuberculosis: a Descriptive Study

Эпидемиология и вакцинопрофилактика, 2018
Background. Extensively drug-resistant tuberculosis (XDR-TB) is a threat to community health. Goal. The estimation of the prevalence of extensively drug-resistant tuberculosis in Omsk region, along with the clinical and epidemiological description of ...
O. A. Pasechnik, A. A. Zimoglyad, I. V. Yarusova, S. V. Vitriv, A. I. Blokh   +4 more
doaj   +1 more source

Extensively Drug-Resistant Tuberculosis (XDR-TB) - A Potential Threat in Ireland [PDF]

The Open Respiratory Medicine Journal, 2007
We describe a case of a 25 year old female from Lithuania who presented with a productive cough. Chest radiograph demonstrated an infiltrate in the left upper lobe and a cavitating lesion in the right middle lobe. Sensitivity testing of her sputum led to a diagnosis of extensively drug-resistant tuberculosis (XDR-TB).
Mc Laughlin, Anne Marie, O’Donnell, Rory A, Gibbons, Noel, Scully, Mary, O’Flangan, Darina, Keane, Joseph   +5 more
openaire   +2 more sources