Results 41 to 50 of about 13,315 (175)

Revisiting Burn Wound Infections: A Comprehensive Review on the Dual Potential of Phages and Probiotics Against Acinetobacter baumannii

Journal of Clinical Laboratory Analysis, EarlyView.
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni, Shahrzad Aliniay Sharafshadehi, Roghayeh Afifirad, Elnaz Bafandeh, Maryam Mokhtaryan, Roya Ghanavati, Atieh Darbandi   +6 more
wiley   +1 more source

Tracking the evolution of an extensively drug-resistant cross-border Mycobacterium tuberculosis cluster, Europe, January 2016 up to August 2025: implications for European surveillance

Eurosurveillance
The emergence and spread of an extensively drug-resistant (XDR) Mycobacterium tuberculosis lineage 4.8 cluster in Europe raises public health concerns.
Daniela Maria Cirillo
doaj   +1 more source

Extensively Drug-Resistant Tuberculosis, Burkina Faso

Emerging Infectious Diseases, 2010
Because data from countries in Africa are limited, we measured the proportion of extensively drug-resistant (XDR) tuberculosis (TB) cases among TB patients in Burkina Faso for whom retreatment was failing.
Nuccia Saleri, Gisèle Badoum, Martial Ouedraogo, Sary M. Dembélé, Rachel Nacanabo, Victor Bonkoungou, Daniela Cirillo, Gabriele Pinsi, Alberto Matteelli   +8 more
doaj   +1 more source

Activity of Semi-Synthetic Mulinanes against MDR, Pre-XDR, and XDR Strains of Mycobacterium tuberculosis

Metabolites, 2021
Tuberculosis causes more than 1.2 million deaths each year. Worldwide, it is the first cause of death by a single infectious agent. The emergence of drug-resistant strains has limited pharmacological treatment of the disease and today, new drugs are ...
María Alejandrina Martínez-González, Luis Manuel Peña-Rodríguez, Andrés Humberto Uc-Cachón, Jorge Bórquez, Mario J. Simirgiotis, Hugo Brígido Barrios-García, Rogelio Hernández-Pando, Luis Alberto Loyola, Carlos Areche, Angel de Jesús Dzul-Beh, Jorge Alberto Barrios-Payán, Dulce Mata-Espinosa, Fabiola Escalante-Erosa, Karlina García-Sosa, Gloria María Molina-Salinas   +14 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Managing a Case of Extensively Drug-Resistant (XDR) Pulmonary Tuberculosis in Singapore

Annals of the Academy of Medicine, Singapore, 2011
Introduction: Extensively drug-resistant tuberculosis (XDR-TB) is an emerging global health risk. We present the first case report of XDR-TB in Singapore. Clinical Picture: A 41-year-old Indonesian lady with previously treated pulmonary tuberculosis presented with chronic cough.
Chee Kiang, Phua, Cynthia B E, Chee, Angeline P G, Chua, Suay Hong, Gan, Aneez D B, Ahmed, Yee Tang, Wang   +5 more
openaire   +2 more sources

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2607-2623, August 2026.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa. [PDF]

PLoS ONE, 2009
The KZN strain family of Mycobacterium tuberculosis is a highly virulent strain endemic to the KwaZulu-Natal region of South Africa, which has recently experienced an outbreak of extensively-drug resistant tuberculosis.
Thomas R Ioerger, Sunwoo Koo, Eun-Gyu No, Xiaohua Chen, Michelle H Larsen, William R Jacobs, Manormoney Pillay, A Willem Sturm, James C Sacchettini   +8 more
doaj   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Two cases of pre-extensively drug resistant tuberculosis in children in Indonesia

Respiratory Medicine Case Reports, 2021
Few reports are available on children with pre-extensively drug-resistant tuberculosis (pre-XDR-TB), which is defined as Mycobacterium tuberculosis resistant to both isoniazid and rifampicin plus resistance to either a fluoroquinolone or a second-line ...
Heda Melinda Nataprawira, Indah Septiane, Sri Sudarwati, Diah Asri Wulandari   +3 more
doaj   +1 more source