Results 11 to 20 of about 103 (99)

Spatial distribution of extensively drug-resistant tuberculosis (XDR TB) patients in KwaZulu-Natal, South Africa.

PLoS ONE, 2017
BackgroundKwaZulu-Natal province, South Africa, has among the highest burden of XDR TB worldwide with the majority of cases occurring due to transmission.
Thandi Kapwata, Natashia Morris, Angela Campbell, Thuli Mthiyane, Primrose Mpangase, Kristin N Nelson, Salim Allana, James C M Brust, Pravi Moodley, Koleka Mlisana, Neel R Gandhi, N Sarita Shah   +11 more
doaj   +1 more source

Selectable Markers for Use in Genetic Manipulation of Extensively Drug-Resistant (XDR) Acinetobacter baumannii HUMC1

mSphere, 2017
Acinetobacter baumannii is one of the most antibiotic-resistant pathogens in clinical medicine, and extensively drug-resistant (XDR) strains are commonly isolated from infected patients.
Brian M. Luna, Amber Ulhaq, Jun Yan, Paul Pantapalangkoor, Travis B. Nielsen, Bryan W. Davies, Luis A. Actis, Brad Spellberg   +7 more
doaj   +1 more source

Combined Resistance to Ceftolozane-Tazobactam and Ceftazidime-Avibactam in Extensively Drug-Resistant (XDR) and Multidrug-Resistant (MDR) Pseudomonas aeruginosa: Resistance Predictors and Impact on Clinical Outcomes Besides Implications for Antimicrobial Stewardship Programs

Antibiotics, 2021
A retrospective case-control study was conducted at Modena University Hospital from December 2017 to January 2019 to identify risk factors and predictors of MDR/XDR Pseudomonas aeruginosa (PA) isolation with resistance to ceftazidime/avibactam (CZA) and ...
Marianna Meschiari, Gabriella Orlando, Shaniko Kaleci, Vincenzo Bianco, Mario Sarti, Claudia Venturelli, Cristina Mussini   +6 more
doaj   +1 more source

Genome Analysis of the First Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Malaysia Provides Insights into the Genetic Basis of Its Biology and Drug Resistance. [PDF]

PLoS ONE, 2015
The outbreak of extensively drug-resistant tuberculosis (XDR-TB) has become an increasing problem in many TB-burdened countries. The underlying drug resistance mechanisms, including the genetic variation favored by selective pressure in the resistant ...
Chee Sian Kuan, Chai Ling Chan, Su Mei Yew, Yue Fen Toh, Jia-Shiun Khoo, Jennifer Chong, Kok Wei Lee, Yung-Chie Tan, Wai-Yan Yee, Yun Fong Ngeow, Kee Peng Ng   +10 more
doaj   +1 more source

Molecular Evolution of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa Strains From Patients and Hospital Environment in a Prolonged Outbreak

Frontiers in Microbiology, 2019
In this study, we aimed to elucidate a prolonged outbreak of extensively drug-resistant (XDR) Pseudomonas aeruginosa, at two adjacent hospitals over a time course of 4 years.
Michael Buhl, Michael Buhl, Christina Kästle, André Geyer, Ingo B. Autenrieth, Ingo B. Autenrieth, Silke Peter, Silke Peter, Matthias Willmann, Matthias Willmann   +9 more
doaj   +1 more source

Extensively Drug-Resistant (XDR) Enteric Fever in Children

Pakistan Journal of Medicine and Dentistry
Background: Typhoid and paratyphoid fevers are caused by Salmonella enterica subspecies serovars typhi (Salmonella typhi and Paratyphi) and the term enteric fever is generally used to describe both.
Sana Ashraf , Mehtab Hussain, Asma Noreen, Falak Abro, Nadeem Noor, Ramla Rehman   +5 more
doaj   +1 more source

Guava Leaf Extract Exhibits Antimicrobial Activity in Extensively Drug-Resistant (XDR) Acinetobacter baumannii

Molecules
Currently, a global health crisis is being caused by microbial resistance, in which Acinetobacter baumannii plays a crucial role, being considered the highest-priority microorganism by the World Health Organization (WHO) for discovering new antibiotics ...
Daniela Gutierrez-Montiel, Alma L. Guerrero-Barrera, Flor Y. Ramírez-Castillo, Fabiola Galindo-Guerrero, Ingrid G. Ornelas-García, Norma A. Chávez-Vela, Matheus de O. Costa, Francisco J. Avelar-Gonzalez, Adriana C. Moreno-Flores, Erick Vazquez-Pedroza, José M. Arreola-Guerra, Mario González-Gámez   +11 more
doaj   +1 more source

Detection of pelA and associated virulence genes in emerging multidrug- and extensively drug-resistant (MDR and XDR) Pseudomonas aeruginosa isolated from Oreochromis niloticus

Bulgarian Journal of Veterinary Medicine, 2023
Pseudomonas aeruginosa is one of the common pathogens causing serious infections in fish, conse-quently high economic losses in freshwater aquaculture. This study was carried out to investigate the prevalence, antibiotic sensitivity, and distribution of ...
R. M. El-Tarabili, H. M. Eid, H. A. A. Elghayaty , E. M. Zaghloul   +3 more
doaj   +1 more source

Prevalence of multi-drug resistant (MDR) and extensively drug-resistant (XDR) phenotypes of Pseudomonas aeruginosa and Acinetobacter baumannii isolated in clinical samples from Northeast of Iran

BMC Research Notes, 2020
Objective Multi and extensively drug-resistant (MDR and XDR), Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii) are two main causative agents of nosocomial infections leading to increased morbidity and mortality. We aim to
Bahman Mirzaei, Zahra Norouzi Bazgir, Hamid Reza Goli, Fatemeh Iranpour, Fatemeh Mohammadi, Ryhaneh Babaei   +5 more
doaj   +1 more source

Extensively drug-resistant (XDR) Neisseria gonorrhoeae cured with ceftriaxone 2 g intravenous monotherapy in Croatia, March 2026

Eurosurveillance
In early 2026 in Croatia, a male heterosexual patient of Croatian origin was diagnosed with extensively drug-resistant (XDR) gonorrhoea after unprotected vaginal intercourse with a Croatian female. The Neisseria gonorrhoeae HR027 isolate (genomic lineage 
Magnus Unemo
doaj   +1 more source