Results 11 to 20 of about 478 (138)

Multi-drug resistant (MDR) and extensively drug-resistant (XDR) bacteraemia rates among cancer patients in an oncology hospital in eastern India: an 11-year retrospective observational study

Infection Prevention in Practice, 2023
Summary: Background: Trend analysis of bacteraemias caused by multi-drug resistant (MDR) and extensively drug resistant (XDR) bacteria helps to assess efficacy of infection prevention and control (IPC) practices.
Satyam Mukherjee, Maitrayee Sarkar De, Gaurav Goel, Arpita Bhattacharyya, Indranil Mallick, Deepak Dabkara, Jaydip Bhaumik, Manas Kumar Roy, Piyali Bose Majumdar, Soumyadip Chatterji, Sudipta Mukherjee, Sanjay Bhattacharya, Mammen Chandy   +12 more
doaj   +1 more source

A review of clinical profile, complications and antibiotic susceptibility pattern of extensively drug-resistant (XDR) Salmonella Typhi isolates in children in Karachi

BMC Infectious Diseases, 2021
Background Enteric fever is a systemic infection caused by Salmonella enterica serovar Typhi and Salmonella enterica serovar Paratyphi A, B, and C. There is an emergence of Typhoid fever caused by extensively drug-resistant Salmonella Typhi strain called
Saba Shahid, Marvi Mahesar, Nida Ghouri, Saba Noreen   +3 more
doaj   +1 more source

Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 24, Issue 3, Page e50-e52, 2013., 2013
Linezolid is a potentially effective drug for the treatment of patients with drug‐resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom three discontinued treatment because of adverse effects.
Alena Tse-Chang, Dennis Kunimoto, Evelina Der, Rabia Ahmed   +3 more
wiley   +1 more source

Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia. [PDF]

, 2017
BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights the need for more effective control strategies.
Anthony, Richard M, Bergval, Indra L, Clark, Taane G, de Beer, Jessica L, de Zwaan, Rina, Phelan, Jody, Schuitema, Anja R, Sengstake, Sarah, van Soolingen, Dick   +8 more
core   +4 more sources

Combined Resistance to Ceftolozane-Tazobactam and Ceftazidime-Avibactam in Extensively Drug-Resistant (XDR) and Multidrug-Resistant (MDR) Pseudomonas aeruginosa: Resistance Predictors and Impact on Clinical Outcomes Besides Implications for Antimicrobial Stewardship Programs

Antibiotics, 2021
A retrospective case-control study was conducted at Modena University Hospital from December 2017 to January 2019 to identify risk factors and predictors of MDR/XDR Pseudomonas aeruginosa (PA) isolation with resistance to ceftazidime/avibactam (CZA) and ...
Marianna Meschiari, Gabriella Orlando, Shaniko Kaleci, Vincenzo Bianco, Mario Sarti, Claudia Venturelli, Cristina Mussini   +6 more
doaj   +1 more source

The Emergence of Extensively Drug‐Resistant Tuberculosis (TB): TB/HIV Coinfection, Multidrug‐Resistant TB and the Resulting Public Health Threat from Extensively Drug‐Resistant TB, Globally and in Canada

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 18, Issue 5, Page 289-291, 2007., 2007
Resistance to anti‐tuberculosis (TB) drugs continues to present a major challenge to global public health. Resistance usually develops due to inadequate TB management, including improper use of medications, improper treatment regimens and failure to complete the treatment course. This may be due to an erratic supply or a lack of access to treatment, as
Paul E Alexander, Prithwish De
wiley   +1 more source

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]

, 2012
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...
Alfredo Ponce-de-Leon, Andrea Benedetti, Carlos Pérez-Guzmán, Carlton Evans, Carole D. Mitnick, Chen-Yuan Chiang, Chi Chiu Leung, Christophe Lange, David Ashkin, Dennis Falzon, Dick Menzies, Domingo Palmero, Donald Enarson, Eward D. Chan, Geoffrey Pasvol, Giovanni B. Migliori, Giovanni Sotgiu, H. Simon Schaaf, Helen Cox, Hye-Ryoun Kim, Jae-Joon Yim, Jamie N. Bayona, Janice Westenhouse, Jennifer Flood, Jerome Robert, Jiehui Li, Joey Lancaster, Jose Peña, José Sifuentes-Osornio, Katherine Flanagan, Kathy DeRiemer, Kwonjune J. Seung, Leah G. Jarlsberg, Lena Shah, Lia D'Ambrosio, Madhukar Pai, Marcos Burgos, Maria G. Hollm-Delgado, Maria I. D. Quelapio, Maria L. Garcia-Garcia, Mario H. Vargas, Martie Van der Walt, Masa Narita, Matthew J. Strand, Melissa Bauer, Mercedes C. Becerra, Michael D. Iseman, Monika Avendano, Neel Gandhi, Nguyen Huy Dung, Payam Tabarsi, Philly O'Riordan, Pirett Viiklepp, Reuben M. Granich, Rita Banerjee, Robert van Altena, Rosella Centis, Salmaan Keshavjee, Sarah Royce, Sergey P. Mishustin, Seung-kyu Park, Shama D. Ahuja, Sonya S. Shin, Tae Sun Shim, Thelma E. Tupasi, Timothy H. Holtz, Tjip S. Van der Werf, Vaira Leimane, Vija Riekstina, Wiel C. M. de Lange, Wing Wai Yew, Won-Jung Koh, Yuji Shiraishi   +72 more
core   +9 more sources

Spatial distribution of extensively drug-resistant tuberculosis (XDR TB) patients in KwaZulu-Natal, South Africa.

PLoS ONE, 2017
BackgroundKwaZulu-Natal province, South Africa, has among the highest burden of XDR TB worldwide with the majority of cases occurring due to transmission.
Thandi Kapwata, Natashia Morris, Angela Campbell, Thuli Mthiyane, Primrose Mpangase, Kristin N Nelson, Salim Allana, James C M Brust, Pravi Moodley, Koleka Mlisana, Neel R Gandhi, N Sarita Shah   +11 more
doaj   +1 more source

Genome Analysis of the First Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Malaysia Provides Insights into the Genetic Basis of Its Biology and Drug Resistance. [PDF]

PLoS ONE, 2015
The outbreak of extensively drug-resistant tuberculosis (XDR-TB) has become an increasing problem in many TB-burdened countries. The underlying drug resistance mechanisms, including the genetic variation favored by selective pressure in the resistant ...
Chee Sian Kuan, Chai Ling Chan, Su Mei Yew, Yue Fen Toh, Jia-Shiun Khoo, Jennifer Chong, Kok Wei Lee, Yung-Chie Tan, Wai-Yan Yee, Yun Fong Ngeow, Kee Peng Ng   +10 more
doaj   +1 more source

Diagnosing tuberculosis in the 21st century – Dawn of a genomics revolution? [PDF]

, 2016
Tuberculosis (TB) ranks alongside HIV as the leading cause of death worldwide, killing 1.5 million people in 2014. Traditional laboratory techniques do not provide sufficiently rapid results to inform clinicians on appropriate treatment, especially in ...
Almeida Da Silva, Ashton, Ashton, Bates, Bates, Bertelli, Bjorn-Mortensen, Black, Boehme, Bradley, Brown, Bryant, Cole, Coll, Coscolla, Didelot, Dinnes, Donoghue, Doughty, Eyre, Farhat, FIND, Flandrois, Gagneux, Gagneux, Galagan, Gardy, Harris, Hatherell, Kalokhe, Kamerbeek, Kanda, Kay, Kwong, Köser, Laurenzo, Luo, Nair, Niemann, Nikolayevskyy, Notomi, Outhred, O’Grady, Palomino, Pankhurst, Quick, Rasko, Reddington, Roetzer, Sandgren, Sanger, Schmidt, Schürch, Sheppard, Sims, Standards Unit, Microbiology Services, Public Health England, Steingart, Steingart, Supply, Thierry, Thierry, Thierry, Walker, WHO, WHO, WHO, Witney, Wlodarska, Yan, Zhang, Zhang, Zhu, Zumla   +72 more
core   +2 more sources