Results 21 to 30 of about 478 (138)

Response of extensively drug resistant salmonella typhi to treatment with meropenem and azithromycin, in Pakistan [PDF]

, 2020
Introduction: Salmonella Typhi is one of the leading health problems in Pakistan. With the emergence of extensively drug resistant (XDR) Salmonella Typhi, treatment options are limited.
Ahmad, Khalil, Ansari, Sarwat, Lohana, Heeramani, Mukhtar, Aiman, Naveed, Abdullah B, Qamar, Farah Naz, Qureshi, Sonia, Yousafzai, Mohammad Tahir   +7 more
core   +4 more sources

Tebipenem as an oral alternative for the treatment of typhoid caused by XDR salmonella typhi [PDF]

, 2021
Background: Antimicrobial therapy is essential for the treatment of enteric fever, the infection caused by Salmonella serovars Typhi and Paratyphi A. However, an increase in resistance to key antimicrobials and the emergence of MDR and XDR in Salmonella ...
Baker, Stephen, Ballell, Lluis, Dongol, Sabina, Karkey, Abhilasha, Mylona, Elli, Qamar, Farah Naz, Qureshi, Sonia, Thanh, Tuyen Ha, Vinh, Phat Voong, Walson, Judd, Álvaro, Elena Fernández   +10 more
core   +2 more sources

Selectable Markers for Use in Genetic Manipulation of Extensively Drug-Resistant (XDR) Acinetobacter baumannii HUMC1

mSphere, 2017
Acinetobacter baumannii is one of the most antibiotic-resistant pathogens in clinical medicine, and extensively drug-resistant (XDR) strains are commonly isolated from infected patients.
Brian M. Luna, Amber Ulhaq, Jun Yan, Paul Pantapalangkoor, Travis B. Nielsen, Bryan W. Davies, Luis A. Actis, Brad Spellberg   +7 more
doaj   +1 more source

A New Vaccine for Tuberculosis: The Challenges of Development and Deployment. [PDF]

, 2009
Tuberculosis (TB) is one of the world's leading causes of death due to infection and efforts to control TB would be substantially aided by the availability of an improved TB vaccine.
Fletcher, Helen A, Hawkridge, Tony, McShane, Helen   +2 more
core   +1 more source

Multidrug-resistant tuberculosis. [PDF]

, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
McNerney, Ruth, Zager, Ellen M
core   +4 more sources

Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting. [PDF]

, 2014
BACKGROUND: Multidrug- (MDR) and extensively drug resistant (XDR) tuberculosis (TB) presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific and successful XDR-TB strains have been found in circulation for almost two ...
Clark, Taane G, Coll, Francesc, Couto, Isabel, Hill-Cawthorne, Grant A, Jordao, Luisa, Macedo, Rita, Machado, Diana, Mallard, Kim, Maltez, Fernando, McNerney, Ruth, Pain, Arnab, Perdigão, João, Portugal, Isabel, Silva, Carla, Silva, Hugo, Viveiros, Miguel   +15 more
core   +4 more sources

Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences [PDF]

, 2015
Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity ...
Alves, Adriana, Clark, Taane G., Coll, Francesc, Glynn, Judith R., Guerra-Assunção, José Afonso, Hasan, Rumina, Hasan, Zahra, Hill-Cawthorne, Grant, Mallard, Kim, Martin, Nigel, McNerney, Ruth, Miranda, Anabela, Nair, Mridul, Pain, Arnab, Perdigão, João, Portugal, Isabel, Preston, Mark D., Viveiros, Miguel, Warry, Andrew   +18 more
core   +4 more sources

Molecular Evolution of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa Strains From Patients and Hospital Environment in a Prolonged Outbreak

Frontiers in Microbiology, 2019
In this study, we aimed to elucidate a prolonged outbreak of extensively drug-resistant (XDR) Pseudomonas aeruginosa, at two adjacent hospitals over a time course of 4 years.
Michael Buhl, Michael Buhl, Christina Kästle, André Geyer, Ingo B. Autenrieth, Ingo B. Autenrieth, Silke Peter, Silke Peter, Matthias Willmann, Matthias Willmann   +9 more
doaj   +1 more source

Assessing the global risk of typhoid outbreaks caused by extensively drug resistant Salmonella Typhi. [PDF]

, 2023
Since its emergence in 2016, extensively drug resistant (XDR) Salmonella enterica serovar Typhi (S. Typhi) has become the dominant cause of typhoid fever in Pakistan. The establishment of sustained XDR S.
Baker, Stephen, Bogoch, Isaac I, Carey, Megan, Chaguza, Chrispin, Grubaugh, Nathan D, Khan, Kamran, Pitzer, Virginia E, Walker, Joseph   +7 more
core   +2 more sources

Prevalence of multi-drug resistant (MDR) and extensively drug-resistant (XDR) phenotypes of Pseudomonas aeruginosa and Acinetobacter baumannii isolated in clinical samples from Northeast of Iran

BMC Research Notes, 2020
Objective Multi and extensively drug-resistant (MDR and XDR), Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii) are two main causative agents of nosocomial infections leading to increased morbidity and mortality. We aim to
Bahman Mirzaei, Zahra Norouzi Bazgir, Hamid Reza Goli, Fatemeh Iranpour, Fatemeh Mohammadi, Ryhaneh Babaei   +5 more
doaj   +1 more source