Results 101 to 110 of about 1,020,393 (303)
Evaluation of the 20,000 days campaign [PDF]
The aim of Counties Manuaku District Health Board (CMDHB) 20,000 Days Campaign was to give back to the community 20,000 healthy and well days to avoid predicted growth in hospital bed days.
Jacqueline Cumming +3 more
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Do changing diagnostic criteria for gestational diabetes influence pregnancy outcome?
The incidence of pregnancy related diabetes has been steadily increasing during the past decade. The aim of this retrospective study was to evaluate the type and prevalence of gestational diabetes complications after implementing new diagnostic criteria ...
Ivka Djaković +5 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Findings brief : external review of the Peace, Conflict and Development Program
French version available in IDRC Digital Library: Constatations en bref de l'examen externe du programme Paix, conflits et développementThis findings brief is based on the reports "External Review of IDRC's Peace, Conflict, and Development Program" by ...
IDRC. Evaluation Unit
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Conducting and Using Evaluability Assessments within CGIAR: CGIAR Evaluation Guidelines
In 2022, the CGIAR System Council and Board approved a CGIAR Evaluation Framework and a revised Evaluation Policy. Their development followed a consultative, inclusive, and iterative approach that included strategic and operational discussions with ...
CGIAR Independent Advisory and Evaluation Service
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
External school evaluation : teachers’ perspectives : two case studies from Northern Portugal [PDF]
The external evaluation of non-higher education schools in Portugal has been developed by the General Inspectorate of Education since 2006. A first cycle of evaluation was completed, covering all educational units in continental Portugal up to 2011.
Seabra, Filipa, Morgado, José Carlos
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source

