Results 111 to 120 of about 1,020,393 (303)

External school evaluation in Portugal: a glance at the impacts on curricular and pedagogical practices [PDF]

open access: yes, 2013
Answering demands for an increase of accountability in terms of public education, and intending to lead to an improvement of the quality of education (Conselho Nacional de Educação, 2010), external school evaluation has been taking place in the ...
Leite, Carlinda   +7 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Incorporating external effects in economic evaluation: The case of smoking

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The aim of this thesis is to explore methods to incorporate external effects on decision making of public health programmes in a UK setting, using smoking ...
Trapero-Bertran, Marta
core  

Liberia Country Program Evaluation 2004-2011 : Evaluation of the World Bank Group Program

open access: yes, 2012
This report evaluates the outcomes of World Bank Group support to Liberia from its post-war reengagement in 2003 through 2011. The country has moved from total disarray to a solid foundation for inclusive
Independent Evaluation Group
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Tipologii ale evaluării în procesul politicilor publice

open access: yesRevista Transilvană de Ştiinţe Administrative, 2012
The enforcement of the judicial decisions is based on the legality principle, all the proceedings, the authorities entitled to perform in this field, the rights of the participants being provided by the law.
Dorina ŢICU
doaj  

Hyperspectral Vectors for Machine Learning Segmentation of Stained and Unstained Cells From Serous Cavity Effusions

open access: yesIEEE Photonics Journal
In addition to information about cell morphology, hyperspectral images (HSIs) provide consistent spectral details across hundreds of wavelengths. Cytological analysis of samples extracted from serous cavity effusions is used to diagnose their benign or ...
Mihaela-Andreea Ilisanu   +8 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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