Results 61 to 70 of about 6,595,667 (193)
Unrelenting Fear Under Stress: Neural Circuits and Mechanisms for the Immediate Extinction Deficit
Frontiers in Systems Neuroscience, 2022 Therapeutic interventions for disorders of fear and anxiety rely on behavioral approaches that reduce pathological fear memories. For example, learning that threat-predictive stimuli are no longer associated with aversive outcomes is central to the ...
Stephen Maren
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Discrimination learning and extinction in toads1 [PDF]
Psychonomic Science, 1969 Toads (Bufo woodhousii woodhousii and Bufo valliceps) were trained for position discrimination in a T maze. One hundred-ninety acquisition trials were followed by 40 extinction trials. The curve obtained differed somewhat from the usual mammalian results.
Philip K. Chu, Garvin McCain
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, 2017 Exposure-based treatments, such as cognitive behavioural therapy (CBT), are leading psychological treatments for anxiety disorders. However, non-response and relapse are common.
Waters, Allison M +3 more
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Explaining the effectiveness of fear extinction through latent-cause inference
, 2021 Acquiring fear responses to predictors of aversive outcomes is crucial for survival. At the same time, it is important to be able to modify such associations when they are maladaptive, for instance in treating anxiety and trauma-related disorders ...
Marie-H. Monfils +3 more
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Frontiers in Synaptic Neuroscience, 2021 The ability to extinguish fear memories when threats are no longer present is critical for adaptive behavior. Fear extinction represents a new learning process that eventually leads to the formation of extinction memories.
Ximena I. Salinas-Hernández +1 more
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Cholinergic neurotransmission in the basolateral amygdala during cued fear extinction
Neurobiology of Stress, 2020 Cholinergic neuromodulation plays an important role in numerous cognitive functions including regulating arousal and attention, as well as associative learning and extinction processes.
Devin M. Kellis +4 more
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Calcineurin Participation in Hebbian and Homeostatic Plasticity Associated With Extinction
Frontiers in Cellular Neuroscience, 2021 In nature, animals need to adapt to constant changes in their environment. Learning and memory are cognitive capabilities that allow this to happen. Extinction, the reduction of a certain behavior or learning previously established, refers to a very ...
Salma E. Reyes-García +1 more
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The role of expectancy violation in extinction learning: a two-day online fear conditioning study
, 2021 According to the inhibitory learning model, expectancy violation drives the formation of CS-no US associations during extinction learning. In this two-day online fear conditioning study, we plan to experimentally manipulate the amount of expectancy ...
Yannik Stegmann, Daniel Gromer
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Distinct representational properties of cues and contexts shape fear and reversal learning
eLifeWhen we learn that something is dangerous, a fear memory is formed. However, this memory is not fixed and can be updated through new experiences, such as learning that the threat is no longer present.
Antoine Bouyeure +6 more
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Fear extinction learning modulates large-scale brain connectivity
NeuroImage, 2021 Exploring the neural circuits of the extinction of conditioned fear is critical to advance our understanding of fear- and anxiety-related disorders. The field has focused on examining the role of various regions of the medial prefrontal cortex, insular ...
Zhenfu Wen +2 more
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