Results 71 to 80 of about 6,595,667 (193)
Opioid receptor antagonists, particularly naltrexone and nalmefene, are among the best-supported pharmacotherapies for alcohol use disorder (AUD), yet their clinical efficacy remains modest and highly heterogeneous. The mechanisms through which transient
Iiro P. Jääskeläinen
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Fear extinction learning and anandamide: an fMRI study in healthy humans
Anxiety- and trauma-related disorders are severe illnesses with high prevalence. Current treatment options leave room for improvement and the endocannabinoid system (ECS) has become a key target in psychopharmacological research. Rodent models suggest an
Jennifer Spohrs +7 more
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IntroductionThe hippocampal formation exhibits complex and context-dependent activity patterns and dynamics, e.g., place cell activity during spatial navigation in rodents or remapping of place fields when the animal switches between contexts ...
David Kappel, Sen Cheng
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Background The amygdala plays a key role in fear learning and extinction and has emerged as an important node of emotional-affective aspects of pain and pain modulation.
Guangchen Ji +4 more
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Implications of extinction in law: Preventing, declaring and learning from species extinctions
Abstract Biodiversity laws around the world differ, but, at their core, these laws promote the fundamental objective of preventing environmental decline and species extinctions. A variety of legal mechanisms have been implemented in domestic laws around the world to achieve this objective, including protection for habitat ...
openaire +3 more sources
Extinction serves as the leading theoretical framework and experimental model to describe how learned behaviors diminish through absence of anticipated reinforcement.
Niv, Yael +7 more
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Dysfunction in corticolimbic circuits that mediate the extinction of learned fear responses is thought to underlie the perseveration of fear in stress-related psychopathologies, including post-traumatic stress disorder.
Kelly M. Moench +3 more
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The Effect of Anticipatory Anxiety on Fear Extinction Learning [PDF]
Adaptive regulation of fear is dependent on successful fear extinction learning; therefore, investigating factors that both enhance and diminish fear extinction learning is a critical line of research.
Echeverria, Daniela C.
core
According to the inhibitory learning model, expectancy violation drives the formation of CS-no US associations during extinction learning. In this two-day virtual reality fear conditioning study, we plan to experimentally manipulate the amount of ...
Yannik Stegmann, Daniel Gromer
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Dopamine contributes to the regulation of higher order information processing and executive control. It is important for memory consolidation processes, and for the adaptation of learned responses based on experience.
Marion Agnes Emma Andre +1 more
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