Results 31 to 40 of about 481,952 (302)
Evidence for Extracellular ATP as a Stress Signal in a Single-Celled Organism [PDF]
, 2015 ATP is omnipresent in biology and acts as an extracellular signaling molecule in mammals. Information regarding the signaling function of extracellular ATP in single-celled eukaryotes is lacking.
Fountain, Samuel +1 more
core +2 more sources
Plant Signaling & Behavior, 2009 Living organisms acquire or synthesize high energy molecules, which they frugally conserve and use to meet their cellular metabolic demands. Therefore, it is surprising that ATP, the most accessible and commonly utilized chemical energy carrier, is actively secreted to the extracellular matrix of cells.
Stephen Chivasa +6 more
openaire +2 more sources
Mediators of Inflammation, 2015 Low-level-laser therapy (LLLT) is an effective complementary treatment, especially for anti-inflammation and wound healing in which dermis or mucus mast cells (MCs) are involved.
Lina Wang +4 more
doaj +1 more source
Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation [PDF]
, 2018 Neurons require a nearly constant supply of ATP. Glucose is the predominant source of brain ATP, but the direct effects of prolonged glucose deprivation on neuronal viability and function remain unclear.
Mennerick, Steven +3 more
core +3 more sources
Lytic Release of Cellular ATP: Physiological Relevance and Therapeutic Applications
Life, 2021 The lytic release of ATP due to cell and tissue injury constitutes an important source of extracellular nucleotides and may have physiological and pathophysiological roles by triggering purinergic signalling pathways.
Ryszard Grygorczyk +7 more
doaj +1 more source
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress [PDF]
, 2006 We previously demonstrated that insulin has a neuroprotective role against oxidative stress, a deleterious condition associated with diabetes, ischemia, and age-related neurodegenerative diseases.
Duarte, Ana I. +4 more
core +2 more sources
Phosphorylation-mediated regulation of integrin-linked kinase 5 by purinoreceptor P2K2
Plant Signaling & Behavior, 2023 Extracellular ATP (eATP) in plants plays a crucial role as a ligand for purinoreceptors, mediating purinergic signaling and regulating diverse biological functions, including responses to abiotic and biotic stresses.
Daewon Kim, Gary Stacey
doaj +1 more source
Calcium-sensing receptor activation increases cell-cell adhesion and ß-cell function [PDF]
, 2012 Background/Aims: The extracellular calcium-sensing receptor (CaR) is expressed in pancreatic β-cells where it is thought to facilitate cell-to-cell communication and augment insulin secretion.
Bennett, J. +5 more
core +2 more sources
Energy-requiring uptake of prostasomes and PC3 cell-derived exosomes into non-malignant and malignant cells [PDF]
Journal of Extracellular Vesicles, 2016 Epithelial cells lining the prostate acini release, in a regulated manner (exocytosis), nanosized vesicles called prostasomes that belong to the exosome family.
Karl Göran Ronquist +9 more
doaj +1 more source
ER localized bestrophin1 activates Ca2+ dependent ion channels TMEM16A and SK4 [PDF]
, 2009 Bestrophins form Ca2+ activated Cl- channels and regulate intercellular Ca2+ signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER), where it physically interacts with stromal interacting molecule 1 (Stim1), the ER ...
Fadi AlDehni +6 more
core +2 more sources