Results 21 to 30 of about 604,290 (256)

Macrophage Response Driven by Extracellular ATP

Biological and Pharmaceutical Bulletin, 2021
The purine nucleotide ATP is a fundamental unit in cellular energy metabolism. Extracellular ATP and its metabolites are also ligands for a family of receptors, known as purinergic receptors, which are expressed ubiquitously in almost every cell type.
Wang, Jing, Takemura, Naoki, Saitoh, Tatsuya   +2 more
openaire   +3 more sources

Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]

, 2012
Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Schmitt, L. Ian, R. E. Sims, Sims, Robert E., P. G. Haydon, Dale, Nicholas, Sims, Robert, Haydon, Philip G, L. I. Schmitt, N. Dale, Schmitt, L Ian   +9 more
core   +1 more source

Activation of retinal glial (Müller) cells by extracellular ATP induces pronounced increases in extracellular H+ flux. [PDF]

PLoS ONE, 2018
Small alterations in extracellular acidity are potentially important modulators of neuronal signaling within the vertebrate retina. Here we report a novel extracellular acidification mechanism mediated by glial cells in the retina. Using self-referencing
Boriana K Tchernookova, Chad Heer, Marin Young, David Swygart, Ryan Kaufman, Michael Gongwer, Lexi Shepherd, Hannah Caringal, Jason Jacoby, Matthew A Kreitzer, Robert Paul Malchow   +10 more
doaj   +1 more source

Temperature-dependent release of ATP from human erythrocytes: Mechanism for the control of local tissue perfusion [PDF]

, 2012
Copyright @ 2012 The AuthorsThis article has been made available through the Brunel Open Access Publishing Fund.Human limb muscle and skin blood flow increases significantly with elevations in temperature, possibly through physiological processes that ...
Gonzalez-Alonso, J, Kalsi, KK
core   +1 more source

Computational prediction and in vitro analysis of the potential ligand binding site within the extracellular ATP receptor, P2K2

Plant Signaling & Behavior, 2023
The plant extracellular ATP (eATP) receptor, P2K2, binds eATP with strong ligand affinity through its extracellular lectin domain. Ligand binding activates the intracellular kinase domain of P2K2 resulting in a variety of intracellular responses and ...
Sung-Hwan Cho, Cuong the Nguyen, an Quoc Pham, Gary Stacey   +3 more
doaj   +1 more source

Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. [PDF]

, 2011
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against disease caused by the bacterium Mycobacterium tuberculosis (M.tb). The efficacy of BCG, especially against pulmonary tuberculosis (TB) is variable. The best
Minassian, Angela M, Pathan, Ansar A, Sander Clare R., Hill, Adrian, Helen A. Fletcher, Fletcher, Helen A, Natalie E R Beveridge, Hill, AVS, Minassian Angela M., Angela M Minassian, Fletcher, HA, Kristin L. Griffiths, Pathan Ansar A., Kristin L Griffiths, Hill, Adrian VS, Griffiths Kristin L., Sander, CR, Hill Adrian V. S., McShane Helen, Beveridge Natalie E. R., Pathan, AA, Minassian, AM, Clare R. Sander, Ansar A. Pathan, Hill, AV, Griffiths, KL, Beveridge, NER, Clare R Sander, Helen McShane, Ansar A Pathan, Beveridge, NE, Natalie E. R. Beveridge, Griffiths , Kristin Lisa, Griffiths, Kristin L, Sander, Clare R, Adrian V S Hill, Adrian V. S. Hill, Helen A Fletcher, Fletcher Helen A., Beveridge, Natalie ER, McShane, H, Fletcher, Helen, Angela M. Minassian, McShane, Helen   +43 more
core   +1 more source

Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]

, 2013
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Peppiatt-Wildman, C. M., C. M. Peppiatt-Wildman, Scott S Wildman, C. Crawford, Wildman, Scott S.P., Kennedy-Lydon, T. M., M. C. Kelly, Wildman, S. S. P., Peppiatt-Wildman, Claire M., S. S. P. Wildman, T. M. Kennedy-Lydon, Kelly, M. C., Crawford, C.   +12 more
core   +1 more source

CMOS-Based Redox-Type Label-Free ATP Image Sensor for In Vitro Sensitive Imaging of Extracellular ATP

Sensors, 2021
Adenosine 5′-triphosphate (ATP) plays a crucial role as an extracellular signaling molecule in the central nervous system and is closely related to various nerve diseases.
Hideo Doi, Tomoko Horio, Yong-Joon Choi, Kazuhiro Takahashi, Toshihiko Noda, Kazuaki Sawada   +5 more
doaj   +1 more source

Phosphorylation-mediated regulation of integrin-linked kinase 5 by purinoreceptor P2K2

Plant Signaling & Behavior, 2023
Extracellular ATP (eATP) in plants plays a crucial role as a ligand for purinoreceptors, mediating purinergic signaling and regulating diverse biological functions, including responses to abiotic and biotic stresses.
Daewon Kim, Gary Stacey
doaj   +1 more source

Extracellular ATP [PDF]

Plant Signaling & Behavior, 2009
Living organisms acquire or synthesize high energy molecules, which they frugally conserve and use to meet their cellular metabolic demands. Therefore, it is surprising that ATP, the most accessible and commonly utilized chemical energy carrier, is actively secreted to the extracellular matrix of cells.
Stephen Chivasa, Daniel F. A. Tomé, Alex M. Murphy, John M. Hamilton, Keith Lindsey, John P. Carr, Antoni R. Slabas   +6 more
openaire   +2 more sources