Results 1 to 10 of about 604,290 (256)
Optical ATP biosensor for extracellular ATP measurement [PDF]
Biosensors and Bioelectronics, 2013 Extracellular Adenosine-5'-triphosphate (ATP) is an important multi-functional molecule which can mediate numerous physiological activities by activating purinergic P2 receptors. The objective of this study was to develop a novel optical ATP sensor for in-situ extracellular ATP measurement in biological tissues.
C, Wang, C-Y C, Huang, W-C, Lin
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Methylene ATP analogs as modulators of extracellular ATP metabolism and accumulation [PDF]
British Journal of Pharmacology, 2004 Transient accumulation of extracellular ATP reflects both release of ATP from intracellular stores and altered rates of ATP metabolism by ecto‐enzymes. Ecto‐nucleoside triphosphate diphosphohydrolases (eNTPDases) and ecto‐nucleotide pyrophosphatases (eNPPs) degrade ATP, while ecto‐nucleotide diphosphokinases (eNDPKs) synthesize ATP from ambient ADP ...
George Dubyak
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Extracellular ATP acts as a damage-associated molecular pattern (DAMP) signal in plants
Frontiers in Plant Science, 2014 As sessile organisms, plants have evolved effective mechanisms to protect themselves from environmental stresses. Damaged (i.e., wounded) plants recognize a variety of endogenous molecules as danger signals, referred to as damage-associated molecular ...
Kiwamu Tanaka +2 more
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Frontiers in Pharmacology, 2017 Extracellular ATP is among molecules promoting microglia activation and inducing the release of extracellular vesicles (EVs), which are potent mediators of intercellular communication between microglia and the microenvironment.
Marta Lombardi +2 more
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Bio-Protocol, 2021 Adenosine 5’-triphosphate (ATP) works as an extracellular signaling molecule for cells in the brain, such as neurons and glia. Cellular communication via release of ATP is involved in a range of processes required for normal brain functions, and aberrant
Nami Kitajima +7 more
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Frontiers in Cellular Neuroscience, 2021 Small alterations in the level of extracellular H+ can profoundly alter neuronal activity throughout the nervous system. In this study, self-referencing H+-selective microelectrodes were used to examine extracellular H+ fluxes from individual astrocytes.
Ji-in Vivien Choi +13 more
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The circadian regulation of extracellular ATP
Purinergic Signalling, 2022 AbstractExtracellular ATP is a potent signaling molecule released from various cells throughout the body and is intimately involved in the pathophysiological functions of the nervous system and immune system by activating P2 purinergic receptors.
Wang, Xin +6 more
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KCl -Permeabilized Pancreatic Islets: An Experimental Model to Explore the Messenger Role of ATP in the Mechanism of Insulin Secretion. [PDF]
PLoS ONE, 2015 Our previous work has demonstrated that islet depolarization with KCl opens connexin36 hemichannels in β-cells of mouse pancreatic islets allowing the exchange of small metabolites with the extracellular medium.
Javier Pizarro-Delgado +4 more
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Extracellular ATP signaling in plants [PDF]
Trends in Cell Biology, 2010 Extracellular adenosine-5′-triphosphate (ATP) induces a number of cellular responses in plants and animals. Some of the molecular components for purinergic signaling in animal cells appear to be lacking in plant cells, although some cellular responses are similar in both systems [e.g.
Tanaka, Kiwamu +3 more
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ATP is an essential autocrine factor for pancreatic β‐cell signaling and insulin secretion
Physiological Reports, 2022 ATP has been previously identified as an autocrine signaling factor that is co‐released with insulin to modulate and propagate β‐cell activity within islets of Langerhans.
Sebastian Hauke +4 more
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