Results 31 to 40 of about 604,290 (256)

Modulation of Extracellular ATP Content of Mast Cells and DRG Neurons by Irradiation: Studies on Underlying Mechanism of Low-Level-Laser Therapy

Mediators of Inflammation, 2015
Low-level-laser therapy (LLLT) is an effective complementary treatment, especially for anti-inflammation and wound healing in which dermis or mucus mast cells (MCs) are involved.
Lina Wang, Lei Hu, Ryszard Grygorczyk, Xueyong Shen, Wolfgang Schwarz   +4 more
doaj   +1 more source

Lytic Release of Cellular ATP: Physiological Relevance and Therapeutic Applications

Life, 2021
The lytic release of ATP due to cell and tissue injury constitutes an important source of extracellular nucleotides and may have physiological and pathophysiological roles by triggering purinergic signalling pathways.
Ryszard Grygorczyk, Francis Boudreault, Olga Ponomarchuk, Ju Jing Tan, Kishio Furuya, Joseph Goldgewicht, Falonne Démèze Kenfack, François Yu   +7 more
doaj   +1 more source

Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex [PDF]

, 2014
Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca2+-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP release from
Lalo, Ulyana, Pankratov, Yuriy, Palygin, Oleg, Oleg Palygin (407627), Philip G Haydon, Ulyana Lalo (506296), Yuriy Pankratov, Seyed Rasooli-Nejad (506297), Rasooli-Nejad, Seyed, Yuriy Pankratov (407630), Oleg Palygin, Ulyana Lalo, Haydon, Philip G., Jemma Andrew, Jemma Andrew (506298), Philip G. Haydon (506299), Andrew, Jemma, Seyed Rasooli-Nejad   +17 more
core   +2 more sources

dATP/ATP, a multifunctional nucleotide, stimulates bacterial cell lysis, extracellular DNA release and biofilm development. [PDF]

PLoS ONE, 2010
Signaling by extracellular adenosine 5'-triphosphase (eATP) is very common for cell-to-cell communication in many basic patho-physiological development processes.
Chuanwu Xi, Jianfeng Wu
doaj   +1 more source

c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells ^†

Cells, 2020
Angiogenic vasa vasorum (VV) expansion plays an essential role in the pathogenesis of hypoxia-induced pulmonary hypertension (PH), a cardiovascular disease.
Derek Strassheim, Vijaya Karoor, Hala Nijmeh, Philip Weston, Martin Lapel, Jerome Schaack, Timothy Sullivan, Edward C. Dempsey, Kurt R. Stenmark, Evgenia Gerasimovskaya   +9 more
doaj   +1 more source

Energy-requiring uptake of prostasomes and PC3 cell-derived exosomes into non-malignant and malignant cells [PDF]

Journal of Extracellular Vesicles, 2016
Epithelial cells lining the prostate acini release, in a regulated manner (exocytosis), nanosized vesicles called prostasomes that belong to the exosome family.
Karl Göran Ronquist, Claire Sanchez, Louise Dubois, Dimitris Chioureas, Pedro Fonseca, Anders Larsson, Anders Ullén, Jeffrey Yachnin, Gunnar Ronquist, Theocharis Panaretakis   +9 more
doaj   +1 more source

Endoplasmic Reticulum Is a Key Organella in Bradykinin-Triggered ATP Release From Cultured Smooth Muscle Cells

Journal of Pharmacological Sciences, 2007
ATP has broad functions as an autocrine/paracrine molecule. The mode of ATP release and its intracellular source, however, are little understood. Here we show that bradykinin via B2-receptor stimulation induces the extracellular release of ATP via the ...
Yumei Zhao, Keisuke Migita, Chiemi Sato, Sadaharu Usune, Takahiro Iwamoto, Takeshi Katsuragi   +5 more
doaj   +1 more source

Activity-dependent adenosine release may be linked to activation of Na+-K+ ATPase : an in vitro rat study [PDF]

, 2014
In the brain, extracellular adenosine increases as a result of neuronal activity. The mechanisms by which this occurs are only incompletely understood. Here we investigate the hypothesis that the Na+ influxes associated with neuronal signalling activate ...
Sims, Robert E., Sims Robert Edward, Dale, Nicholas, Sims, Robert, Dale Nicholas, Robert Edward Sims, Nicholas Dale   +6 more
core   +2 more sources

Extracellular ATP/adenosine dynamics in the brain and its role in health and disease

Frontiers in Cell and Developmental Biology
Extracellular ATP and adenosine are neuromodulators that regulate numerous neuronal functions in the brain. Neuronal activity and brain insults such as ischemic and traumatic injury upregulate these neuromodulators, which exert their effects by ...
Eiji Shigetomi, Eiji Shigetomi, Kent Sakai, Kent Sakai, Schuichi Koizumi, Schuichi Koizumi   +5 more
doaj   +1 more source

Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae

G3: Genes, Genomes, Genetics, 2016
Adenosine triphosphate (ATP) plays an important role as a primary molecule for the transfer of chemical energy to drive biological processes. ATP also functions as an extracellular signaling molecule in a diverse array of eukaryotic taxa in a conserved ...
Theodore W. Peters, Aaron W. Miller, Cendrine Tourette, Hannah Agren, Alan Hubbard, Robert E. Hughes   +5 more
doaj   +1 more source