Results 51 to 60 of about 7,179,267 (297)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Enzyme activity below the dynamical transition at 220K [PDF]

, 1998
Enzyme activity requires the activation of anharmonic motions, such as jumps between potential energy wells. However, in general, the forms and time scales of the functionally important anharmonic dynamics coupled to motion along the reaction coordinate ...
Smith, Jeremy C., Ferrand, Michel, Finney, John L., Dunn, Rachel, Hery, Stephanie, Dunn, Rachel V., Daniel, Roy M., Ferrand M, Daniel RM, Finney J L, Dunn R, Hery S, Smith JC   +12 more
core   +1 more source

Extracellular vesicles derived from macrophages display glycyl-tRNA synthetase 1 and exhibit anti-cancer activity [PDF]

, 2020
Journal of Extracellular Vesicles published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular VesiclesGlycyl-tRNA synthetase 1 (GARS1), a cytosolic enzyme secreted from macrophages, promotes apoptosis in cancer cells ...
Won Suk Yang, Sehyun Chae, Chihong Song, Kim, Byung Gyu, Yong Song Gho, Gho, Yong Song, Hyun, Jae Kyung, Goughnour, Peter C, Yang, Won Suk, Cho, Seongmin, Song, Chihong, Daehee Hwang, Jung, Hyun Suk, Park, Min Chul, Kim, Sunghoon, Jun, Sangmi, Chae, Sehyun, Lee, Ji-Hyun, Hwang, Daehee, Min Chul Park, Ji‐Hyun Lee, Goughnour, Peter C., Lee, Ji‐Hyun, Jae Kyung Hyun, Seongmin Cho, Hyun Suk Jung, Sunghoon Kim, Sangmi Jun, Kim, Sang Bum, Peter C. Goughnour, Sang Bum Kim, Byung Gyu Kim   +31 more
core   +1 more source

PATHOGEN IMPACT ON THE ACTIVITY DYNAMICS OF POTATO SUSPENSION CELLS EXTRA-CELLULAR PEROXIDASE [PDF]

Journal of Stress Physiology & Biochemistry, 2005
Changes in the activity of extracellular peroxidases were measured in cell suspension cultures of potato infected by Clavibacter michiganensis subsp. sepedonicus (Spieck. et Kotth.) Skapt et Burkh.
Graskova I.A., Antipina I.V., Potapenko O.Y., Voinikov V.K.   +3 more
doaj  

Characterization of Hexenuronosyl Xylan-degrading Enzymes Produced by Paenibacillus sp. 07

BioResources, 2016
The enzyme involved in hexenuronic acid (HexA) removal from kraft pulp was identified in Paenibacillus sp. strain 07. Extracellular and intracellular enzymes of Paenibacillus sp. were assessed for their hexenuronosyl-xylotriose (∆X3) degradation activity.
Krisna Septiningrum, Hiroshi Ohi, Akiko Nakagawa-izumi, Akihiko Kosugi   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The use of phenyl-Sepharose for the affinity purification of proteinases [PDF]

, 1993
Phenyl-Sepharose is most often used as an adsorbent for hydrophobic interaction chromatography (HIC). We report on its effective use for the affinity purification of some extracellular thermostable proteinases from bacterial sources.
Prescott, Mark, Peek, Keith, Veitch, Dallas P., Daniel, Roy M.   +3 more
core   +1 more source

Optimization and Characterization of Nicosulfuron-Degrading Enzyme from Bacillus subtilis Strain YB1

Journal of Integrative Agriculture, 2012
A strain of Bacillus subtilis strain YB1, isolated and preserved in our lab., showed a high nicosulfuron-degrading activity. Optimization of culture conditions on production of nicosulfuron-degrading enzyme from Bacillus subtilis strain YB1 was carried ...
Zhan-hai KANG, Jin-gao Dong, Jin-lin ZHANG   +2 more
doaj   +1 more source

Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis. [PDF]

PLoS ONE, 2018
The neurodegenerative disease multiple sclerosis (MS) is pathologically characterized by the massive influx of immune cells into the central nervous system.
Navina L Chrobok, John G J M Bol, Cornelis A Jongenelen, John J P Brevé, Said El Alaoui, Micha M M Wilhelmus, Benjamin Drukarch, Anne-Marie van Dam   +7 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source