Results 71 to 80 of about 8,496,804 (298)

Enzyme activity and dynamics in near-anhydrous conditions [PDF]

, 2009
Water is widely assumed to be essential for life 1, although the exact molecular basis of this requirement is unclear 2-4. Water facilitates protein motions 5-9 and although enzyme activity has been demonstrated at low hydrations in organic solvents 10 ...
John Finney, Moeava Tehei, Vandana Kurkal-Siebert, Jeremy Smith, Murielle Lopez, Rachel Dunn, Roy Daniel   +6 more
core  

Activity-dependent release of Adenosine: a critical re-evaluation of mechanism [PDF]

, 2008
Adenosine is perhaps the most important and universal modulator in the brain. The current consensus is that it is primarily produced in the extracellular space from the breakdown of previously released ATP.
Dale, Nicholas, Wall, Mark J.
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Syndecan-4 regulates cell-surface trafficking and biological activity of transglutaminase-2 [PDF]

, 2009
Transglutaminase-2 (TG2) is a Ca2+-dependent crosslinking enzyme involved in the post-translational modification of proteins via the formation of Nε(γ-glutamyl)lysine isodipeptides.
Scarpellini, A
core  

Purification and Molecular Characterization of Protease from Lacticaseibacillus paracasei IN17 Isolated from Fermented Fish (Inasua)

Biosaintifika: Journal of Biology & Biology Education
Protease is a protein degrading enzyme that is widely used in the food fermentation and protein processing industries. An example of a fermented fish product known as inasua, which originates from Maluku in Indonesia, is a proteolytic bacterial source ...
Sakina Maya Maulawi, Nisa Mubarik, Laksmi Ambarsari   +2 more
doaj   +1 more source

Highly efficient production of transfructosylating enzymes using low-cost sugarcane molasses by A. pullulans FRR 5284

Bioresources and Bioprocessing, 2021
Fructooligosaccharides (FOS) are a type of important prebiotics and produced by transfructosylating enzymes. In this study, sugarcane molasses was used as the substrate for production of transfructosylating enzymes by Aureobasidium pullulans FRR 5284 ...
Most Sheauly Khatun, Morteza Hassanpour, Mark D. Harrison, Robert E. Speight, Ian M. O’Hara, Zhanying Zhang   +5 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Patterns in extracellular enzyme activity and microbial diversity in deep-sea Mediterranean sediments [PDF]

, 2020
Highlights • Explored microbial communities in Mediterranean Sea sediments. • Diversity decreased with greater water depth. • Extracellular enzyme activity was not homogenous within this basin.
Mahmoudi, Nagissa, Hagen, Shane M., Steen, Andrew D, Hazen, Terry C., Steen, Andrew D., Hagen, Shane M, Hazen, Terry C   +6 more
core   +1 more source

Extracellular urease from Arthrobacter sp. strain 169 for enzyme-induced calcium carbonate precipitation (EICP) applications

Annals of Microbiology
Background Enzyme-induced carbonate precipitation (EICP) is a process that promotes calcite formation via urease-mediated hydrolysis of urea, resulting in carbonate ion production in the presence of calcium.
Sahar Salehi, Arezoo Karami, Gholam Reza Ghezelbash   +2 more
doaj   +1 more source

A Novel Extracellular Catalase Produced by the Antarctic Filamentous Fungus Penicillium Rubens III11-2

Fermentation
Catalase (CAT) is an enzyme involved in the first line of cellular antioxidant defense. It plays a key role in the protection of a wide range of Antarctic organisms against cold stress.
Zdravka Koleva, Radoslav Abrashev, Maria Angelova, Galina Stoyancheva, Boryana Spassova, Lyudmila Yovchevska, Vladislava Dishliyska, Jeny Miteva-Staleva, Ekaterina Krumova   +8 more
doaj   +1 more source