Results 61 to 70 of about 2,626,097 (306)

Extracellular Matrix Composition and Remodeling: Current Perspectives on Secondary Palate Formation, Cleft Lip/Palate, and Palatal Reconstruction

Frontiers in Cell and Developmental Biology, 2019
Craniofacial development comprises a complex process in humans in which failures or disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a common congenital anomaly that occurs due to variations in craniofacial ...
Katiúcia Batista Silva Paiva, Clara Soeiro Maas, Pâmella Monique dos Santos, José Mauro Granjeiro, José Mauro Granjeiro, Ariadne Letra, Ariadne Letra, Ariadne Letra   +7 more
doaj   +1 more source

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Biomolecules, 2023
Mineralization-competent cells, including hypertrophic chondrocytes, mature osteoblasts, and osteogenic-differentiated smooth muscle cells secrete media extracellular vesicles (media vesicles) and extracellular vesicles bound to the extracellular matrix (
Saida Mebarek, Rene Buchet, Slawomir Pikula, Agnieszka Strzelecka-Kiliszek, Leyre Brizuela, Giada Corti, Federica Collacchi, Genevieve Anghieri, Andrea Magrini, Pietro Ciancaglini, Jose Luis Millan, Owen Davies, Massimo Bottini   +12 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Brain extracellular matrix [PDF]

Glycobiology, 1996
The extracellular matrix of the adult brain tissue has a unique composition. The striking feature of this matrix is the prominence of lecticans, proteoglycans that contain a lectin domain and a hyaluronic acid-binding domain. Hyaluronic acid and tenascin family adhesive/anti-adhesive proteins are also abundant.
openaire   +2 more sources

Biomechanical assessment of extracellular matrix in native and tissue engineered cartilage across lenght scales [PDF]

, 2012
Musculoskeletal diseases (MSD) and related disorders account for the largest fraction of temporary and permanent disabilities, and are often considered to be an inevitable consequence of aging.
Loparic, Marko
core   +1 more source

Higher hemoglobin levels are associated with adverse heart rate variability in a middle‐aged birth cohort

Physiological Reports
High hemoglobin (Hb) levels within normal variation range are considered beneficial. However, lower Hb levels within normal variation range are associated with healthier cardiovascular traits. Heart rate variability (HRV) and baroreflex sensitivity (BRS)
Samuli Sakko, Mikko. P. Tulppo, Peppi Koivunen, Joona Tapio   +3 more
doaj   +1 more source

Macromolecular crowding and decellularization method increase the growth factor binding potential of cell-secreted extracellular matrices

Frontiers in Bioengineering and Biotechnology, 2023
Recombinant growth factors are used in tissue engineering to stimulate cell proliferation, migration, and differentiation. Conventional methods of growth factor delivery for therapeutic applications employ large amounts of these bioactive cues. Effective,
Shierly W. Fok, Robert C. H. Gresham, Weston Ryan, Benjamin Osipov, Chelsea Bahney, J. Kent Leach, J. Kent Leach   +6 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

CONSTRUCTIVE TISSUE REMODELING BY EXTRACELLULAR MATRIX BIOSCAFFOLDS WITHIN THE AGING SKELETAL MUSCLE MICROENVIRONMENT [PDF]

, 2013
Adult mammalian skeletal muscle tissue retains inherent regenerative capability in response to injury. This regenerative response is contingent upon an activated progenitor cell population and a temporal transition from pro-inflammatory M1 to ...
Sicari, Brian
core  

Modulation of cell-matrix adhesions to affect mechanotransduction [PDF]

, 2010
In cultured fibroblasts three types of cell-matrix adhesion with specific cellular localization and protein composition can be distinguished: focal complexes, focal adhesions and fibrillar adhesions.
Lutz, Roman
core   +1 more source