Results 61 to 70 of about 848,932 (314)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Understanding the extracellular matrix [PDF]
Journal of Periodontal & Implant Science, 2013 Tissue engineering deals with the growth and regeneration techniques of connective tissues or organs from a combination of cells and a scaffold to produce a functional organ. The engineering techniques therefore begin with an implantation of artificial materials, providing a proper environment for cells or tissues to be grown and functionalized.
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Silicon and the Plant Extracellular Matrix [PDF]
Frontiers in Plant Science, 2016 Silicon (Si) is one of the most abundant elements on earth. Although not considered essential for the growth and development of higher plants, it is nonetheless known to increase vigor and to play protective roles. Its protective effects include for instance alleviation of (a)biotic stress damages and heavy metal toxicity. Si was shown to interact with
Guerriero, Gea +2 more
openaire +3 more sources
, 2012 Throughout pregnancy the cytotrophoblast, the stem cell of the placenta, gives rise to the differentiated forms of trophoblasts. The two main cell lineages are the syncytiotrophoblast and the invading extravillous trophoblast.
Dash, Philip R., Patel, Anand
core +1 more source
Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom-induced glomerulonephritis [PDF]
, 2012 We investigated the mechanism of development and repair process of glomerular injury in a rat model of habu snake (Trimeresurus flavoviridis) venom (HSV)-induced glomerulonephritis. Glomerulonephritis was induced in rats by intravenously injecting HSV at
Miyazaki, Masanobu +7 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Atherosclerosis and Extracellular Matrix
Journal of Atherosclerosis and Thrombosis, 2003 Atherosclerosis is primarily a lesion that progresses due to a series of reactions that are induced by repair of injured intima. The intercellular networking that occurs among smooth muscle cells, macrophages, T lymphocytes and endothelial cells leads to a fibroproliferative response, in which the extracellular matrix (ECM) plays an important role. The
Katsuda, Shogo, Kaji, Toshiyuki
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Extracellular matrix and the neural stem cell niche
, 2011 Basal lamina is present in many stem cell niches, but we still have a poor understanding of the role of this and other extracellular matrix (ECM) components.
Kazanis, I.
core +1 more source
Autologous Versatile Vesicles‐Incorporated Biomimetic Extracellular Matrix Induces Biomineralization
, 2020 Restoring extracellular matrix (ECM) with supportive and osteoinductive abilities is of great significance for bone tissue regeneration. Current approaches involving cell-based scaffolds or nanoparticle-modified biomimic-ECM have been met with additional
Zhang, Yufeng +17 more
core +1 more source