Results 1 to 10 of about 192,244 (159)
The Role of Extracellular Matrix (ECM) Adhesion Motifs in Functionalised Hydrogels. [PDF]
Molecules, 2023 To create functional tissue engineering scaffolds, biomaterials should mimic the native extracellular matrix of the tissue to be regenerated. Simultaneously, the survival and functionality of stem cells should also be enhanced to promote tissue organisation and repair.
Morwood AJ +3 more
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Heparanase: A Multitasking Protein Involved in Extracellular Matrix (ECM) Remodeling and Intracellular Events [PDF]
Cells, 2018 Heparanase (HPSE) has been defined as a multitasking protein that exhibits a peculiar enzymatic activity towards HS chains but which simultaneously performs other non-enzymatic functions.
Valentina Masola +3 more
doaj +2 more sources
Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives. [PDF]
Compr Physiol, 2023 AbstractFibrosis in adipose tissue is a major driver of obesity‐related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy expansion of adipose tissue in response to over nutrition. In obese adipose‐depots, hypoxia stimulates multiple pro‐fibrotic signaling pathways in different cell ...
Sun K, Li X, Scherer PE.
europepmc +3 more sources
Human extracellular matrix (ECM)-like collagen and its bioactivity. [PDF]
Regen BiomaterAbstract Collagen, the most abundant structural protein in the human extracellular matrix (ECM), provides essential support for tissues and guides tissue development. Despite its widespread use in tissue engineering, there remains uncertainty regarding the optimal selection of collagen sources. Animal-derived sources pose challenges such
Zhou H +6 more
europepmc +3 more sources
The Extracellular Matrix, the Silent ‘Architect’ of Glioma [PDF]
BiomedicinesThe brain’s extracellular matrix (ECM) serves as a dynamic and instructive regulator of glioma progression. The ECM provides structural support while integrating pharmacological and mechanical signals that influence glioma initiation, progression, and ...
Carmen Rubio +5 more
doaj +2 more sources
Extracellular Matrix (ECM) [PDF]
, 2012 The region of space at the periphery of cyanobacterial cells is the interface between the environment and intracellular processes. This metaspace may include a structure appressed to the outer wall and membrane, such as an extracellular polysaccharide (EPS), a structural and/or physiological discontinuity in the control of flow metabolites, as well as ...
Helm R.F., Potts M.
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Development potential of extracellular matrix hydrogels as hemostatic materials
Frontiers in Bioengineering and Biotechnology, 2023 The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular matrix proteins are unable to cover the wound, making it ...
Dan Cai, Wei Weng
doaj +1 more source
Extracellular Vesicles as Regulators of the Extracellular Matrix
Bioengineering, 2023 Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication.
Neil J. Patel +2 more
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Matrix Biology Plus, 2023 The healthy skeletal muscle extracellular matrix (ECM) has several functions including providing structural integrity to myofibers, enabling lateral force transmission, and contributing to overall passive mechanical properties.
Ross P. Wohlgemuth +5 more
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Interplay between Extracellular Matrix and Neutrophils in Diseases
Journal of Immunology Research, 2021 The extracellular matrix (ECM) is a highly dynamic and complex network structure, which exists in almost all tissues and is the microenvironment that cells rely on for survival.
Yanyan Zhu +6 more
doaj +1 more source