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Is extracellular matrix (ECM) a promising scaffold biomaterial for bone repair?

Histology and histopathology, 2021
The increasing demand for bone grafts and the scarcity of donors worldwide are promoting researchers to seek alternatives. The extracellular matrix (ECM) has been reported to enhance properties of osteoconduction and osteoinduction by simulating the molecular structure of bone and facilitating cell infiltration for bone repair.
Ranli, Gu   +5 more
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Extracellular Matrix (ECM) and the Sculpting of Embryonic Tissues

2018
Extracellular matrices (ECMs) are structurally and compositionally diverse networks of collagenous and noncollagenous glycoproteins, glycosaminoglycans, proteoglycans, and associated molecules that together comprise the metazoan matrisome. Proper deposition and assembly of ECM is of profound importance to cell proliferation, survival, and ...
Bette J, Dzamba, Douglas W, DeSimone
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Reactive production of extracellular matrix (ECM) by corneal endothelial cells

Acta Ophthalmologica, 1992
Abstract. Results of experimental and histopathological studies of reactive production of extracellular matrix by corneal endothelial cells are summarized and evaluated. In anterior synechiae, epithelial ingrowth and a chronic corneal ulcer extracellular matrix was produced not only toward Descemet's membrane but also on the normally free endothelial ...
Z, Zagórski, G O, Naumann
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The Extracellular Matrix (ECM) and Wound Healing: A Review

2023
The purpose of this article is to summarize current and historical literature demonstrating the role of the Extracellular Matrix (ECM) in the various stages of the wound healing cascade. ECM is a three-dimensional framework that is found in all human tissues.
Diller, Robert B, Tabor, Aaron J
openaire   +2 more sources

Dentin Extracellular Matrix (ECM) Proteins: Comparison to Bone ECM and Contribution to Dynamics of Dentinogenesis

Connective Tissue Research, 2003
Dentinogenesis involves the initial odontoblastic synthesis of a collagen-rich extracellular matrix (ECM) and predentin that is converted to dentin when the collagen fibrils become mineralized. Since the width of predentin is rather uniform, we postulate that extracellular events regulate dentinogenesis.
William T, Butler   +2 more
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pan-ECM: live brain extracellular matrix imaging with protein-reactive dye

2023
AbstractThe brain extracellular matrix (ECM), consisting of proteins and glycosaminoglycans, is a critical scaffold in the development, homeostasis, and disorders of the central nervous system (CNS) and undergoes remodeling in response to environmental cues.
Xiaoqian Ge   +9 more
openaire   +2 more sources

Different Role of Extracellular Matrix (ECM) in Brain: Review

SSRN Electronic Journal, 2021
This Review article gives you important information of the different qualitative and quantitative composition of the extracellular matrix (ECM) & how it play a vital role for the proper function of the brain. This paper is also shows how ECM has interact with central nervous system & its association with various Neurological Disorders.
openaire   +1 more source

Extracellular Matrix (ECM) Proteoglycans Produced by Cultured Bovine Corneal Endothelial Cells

Connective Tissue Research, 1984
The nature of the proteoglycan(s) (PG) found in the extracellular matrix (ECM) layer produced by cultured bovine corneal endothelial (BCE) cells is analyzed. The PG(s) account for approximately 5 to 6% of the dry weight of the ECM, regardless of the amount of extracellular soluble PG available in the medium. A 4 M guanidinium chloride (GuCl) extract of
Z, Nevo, R, Gonzalez, D, Gospodarowicz
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Extracellular Matrix Proteome: Isolation of ECM Proteins for Proteomics Studies

2019
Understanding molecular mechanisms and cellular metabolism in varied plant processes necessitates knowledge of the expressed proteins and their subcellular distribution. Spatial partitioning of organelles generates an enclosed milieu for physiochemical reactions designed and tightly linked to a specific organelle function.
Eman, Elagamey   +3 more
openaire   +2 more sources

Extracellular matrix (ECM)‐stiffness regulated cancer cell (A549) migration

The FASEB Journal, 2016
Extracellular matrix (ECM)‐stiffness is one of the potent regulator of cell physiology such as proliferation, morphology, and migration. From previous studies, it has been known that tumor develops increased collagen deposition at the surrounding tissues.
Bomi Gweon   +4 more
openaire   +1 more source

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