Results 91 to 100 of about 2,138,893 (293)

Bacteriodes fragilis interactions with the collagen type I component of the host extracellular matrix [PDF]

open access: yes, 2010
Includes bibliographical references (p. 116-126).Bacteroides fragilis is an opportunistic pathogen which can cause life threatening infections in humans and animals.
Galvao, Bruna Patricia Gomes de Vasconcelos
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies

open access: yesNature Communications, 2020
The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.
Di-Wei Zheng   +8 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Extracellular matrix in ovarian follicular development and disease

open access: yes, 2005
The original publication is available at www.springerlink.comThe ovarian follicle contains several different cell types and separate compartments and undergoes substantial development during its growth and maturation.
Rodgers, R.   +3 more
core   +1 more source

Summary of genes encoding extracellular matrix (ECM) components involved in rapid growth.

open access: yes, 2020
Summary of genes encoding extracellular matrix (ECM) components involved in rapid growth.
Jiancheng Zhai (6039314)   +3 more
core   +1 more source

Extracellular matrix and perineuronal nets in neural plasticity, memory, and epileptogenesis

open access: yesFrontiers in Molecular Neuroscience
In the mature brain, the extracellular matrix (ECM) molecules derived from neurons and glia accumulate in spatially distinct extracellular compartments, including a diffuse interstitial matrix and condensed perineuronal nets (PNNs), where they regulate ...
Hanxiao Zhu   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

The complex interplay between extracellular matrix and cells in tissues

open access: yes, 2019
Extracellular matrix (ECM) maintains the structural integrity of tissues and regulates cell and tissue functions. ECM is comprised of fibrillar proteins, proteoglycans (PGs), glycosaminoglycans, and glycoproteins, creating a heterogeneous but well ...
Cristina Giaroni   +17 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

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