Results 61 to 70 of about 2,138,893 (293)

High-yield cell-derived extracellular matrix bioink via macromolecular crowding for versatile 3D bioprinting

Materials Today Bio
Decellularized extracellular matrix (dECM) is a promising bioink because it replicates the biochemical and structural features of native tissues. However, tissue-derived dECM is limited by restricted availability and potential immunogenicity. To overcome
Siwi Setya Utami, Honghyun Park, Jueun Kim, Aram Sung, Min-Ju Choi, Ga-Hee Ryoo, Chang Woo Gal, Insup Kim, Hui-Suk Yun, Yeong-Jin Choi   +9 more
doaj   +1 more source

Proteolytic Regulation of Synaptic Plasticity in the Mouse Primary Visual Cortex: Analysis of Matrix Metalloproteinase 9 Deficient Mice.

Frontiers in Cellular Neuroscience, 2015
The extracellular matrix (ECM) is known to play important roles in regulating neuronal recovery from injury. The ECM can also impact physiological synaptic plasticity, although this process is less well understood.
Emily A Kelly, Amanda S Russo, Cory D Jackson, Cassandra E Lamantia, Ania K Majewska   +4 more
doaj   +1 more source

Extracellular Matrix Enzymes and Immune Cell Biology

Frontiers in Molecular Biosciences, 2021
Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM metalloproteinases, including Matrix Metalloproteinases (MMPs), A Disintegrin and Metalloproteinases ...
Meagan McMahon, Siying Ye, Jess Pedrina, Daniel Dlugolenski, John Stambas   +4 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

ELFN1 is a new extracellular matrix (ECM)-associated protein

Life Sciences
The ELFN1, discovered in 2007, is a single-pass transmembrane protein. Studies conducted thus far to elucidate the function of the Elfn1 have been limited only to animal studies. These studies have reported that ELFN1 is a universal binding partner of metabotropic glutamate receptors (mGluRs) in the central nervous system and its functional deficiency ...
Selda Ayhan, Ali Dursun
openaire   +4 more sources

Combination of cell immortalization and apoptosis induction to engineer decellularized matrices as bone graft materials [PDF]

, 2013
Infection, trauma or tumors can generate critical bone defects in which the regeneration is compromised, thus necessitating the development of suitable repair strategies.
Bourgine, Paul
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Extracellular matrix and the neural stem cell niche

, 2011
Basal lamina is present in many stem cell niches, but we still have a poor understanding of the role of this and other extracellular matrix (ECM) components.
Kazanis, I.
core   +1 more source

Antibodies and methods for immunohistochemistry of extracellular matrix proteins

, 2020
The diversity of extracellular matrix (ECM) proteins encoded in mammalian genomes and detected by proteomic analyses generates a need for well validated antibodies against these proteins.
Rickelt, Steffen, Hynes, Richard O
core   +1 more source

Light-Sheet Scattering Microscopy to Visualize Long-Term Interactions Between Cells and Extracellular Matrix

Frontiers in Immunology, 2022
Visualizing interactions between cells and the extracellular matrix (ECM) mesh is important to understand cell behavior and regulatory mechanisms by the extracellular environment.
Xiangda Zhou, Renping Zhao, Archana K. Yanamandra, Archana K. Yanamandra, Markus Hoth, Bin Qu, Bin Qu   +6 more
doaj   +1 more source