Phylobone: a comprehensive database of bone extracellular matrix proteins in human and model organisms [PDF]
Bone Research, 2023 The bone extracellular matrix (ECM) contains minerals deposited on highly crosslinked collagen fibrils and hundreds of non-collagenous proteins. Some of these proteins are key to the regulation of bone formation and regeneration via signaling pathways ...
Margalida Fontcuberta-Rigo +2 more
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Extracellular Matrix Proteins Improve Risk Prediction in Patients Undergoing Transcatheter Aortic Valve Replacement. [PDF]
J Am Heart AssocBoeckling F +9 more
europepmc +2 more sources
Development potential of extracellular matrix hydrogels as hemostatic materials
Frontiers in Bioengineering and Biotechnology, 2023 The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular matrix proteins are unable to cover the wound, making it ...
Dan Cai, Wei Weng
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Frontiers in Bioengineering and Biotechnology, 2022 The absence or damage of a tissue is the main cause of most acute or chronic diseases and are one of the appealing challenges that novel therapeutic alternatives have, in order to recover lost functions through tissue regeneration.
Víctor Alfonso Solarte David +6 more
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Extracellular Targets to Reduce Excessive Scarring in Response to Tissue Injury
Biomolecules, 2023 Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite extensive studies to define valid anti-fibrotic targets and develop effective therapeutics, progressive fibrosis remains a significant medical problem ...
Jolanta Fertala +6 more
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The functional role of soluble proteins acquired by extracellular vesicles
Journal of Extracellular Biology, 2022 Extracellular vesicles (EVs) are lipid bilayer‐enclosed nanosized particles released by all cell types during physiological as well as pathophysiological processes to carry out diverse biological functions, including acting as sources of cellular dumping,
Ana Paula Ramos +7 more
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Natural biopolymer-based hydrogels as designer matrices for organoid cultures [PDF]
Organoid, 2023 Matrigel, a mouse sarcoma-derived extract, is considered the gold standard for organoid cultures. However, it has several drawbacks, including inconsistent and ill-defined composition, varying quality between batches, and potential cancer-related health ...
Yun Kee Jo
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Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
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Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity
Scientific Reports, 2021 Obesity and the metabolic disease epidemic has led to an increase in morbidity and mortality. A rise in adipose thermogenic capacity via activation of brown or beige fat is a potential treatment for metabolic diseases.
Maria A. Gonzalez Porras +10 more
doaj +1 more source
The Extracellular Matrix of Staphylococcus aureus Biofilms Comprises Cytoplasmic Proteins That Associate with the Cell Surface in Response to Decreasing pH [PDF]
, 2014 Biofilm formation by Staphylococcus aureus involves the formation of an extracellular matrix, but the composition of this matrix has been uncertain. Here we report that the matrix is largely composed of cytoplasmic proteins that reversibly associate with
DeFrancesco, Alicia S. +3 more
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