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Phylobone: a comprehensive database of bone extracellular matrix proteins in human and model organisms [PDF]
Bone Research, 2023 The bone extracellular matrix (ECM) contains minerals deposited on highly crosslinked collagen fibrils and hundreds of non-collagenous proteins. Some of these proteins are key to the regulation of bone formation and regeneration via signaling pathways ...
Margalida Fontcuberta-Rigo +2 more
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MALDI mass spectrometry imaging of extracellular matrix proteins. [PDF]
AnalystMass spectrometry (MS) imaging is a powerful method for assessing spatial distributions of biomolecules in tissues. This perspective highlights the challenges and opportunities for MS imaging of extracellular matrix protein distributions.
Rampal A, Peyton SR, Vachet RW.
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Thymic "nurse" cells express extracellular matrix proteins [PDF]
Memorias do Instituto Oswaldo Cruz, 1991 Dea Maria S. Villa-Verde, Wilson Savino
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Development potential of extracellular matrix hydrogels as hemostatic materials
Frontiers in Bioengineering and Biotechnology, 2023 The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular matrix proteins are unable to cover the wound, making it ...
Dan Cai, Wei Weng
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Frontiers in Bioengineering and Biotechnology, 2022 The absence or damage of a tissue is the main cause of most acute or chronic diseases and are one of the appealing challenges that novel therapeutic alternatives have, in order to recover lost functions through tissue regeneration.
Víctor Alfonso Solarte David +6 more
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Extracellular Targets to Reduce Excessive Scarring in Response to Tissue Injury
Biomolecules, 2023 Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite extensive studies to define valid anti-fibrotic targets and develop effective therapeutics, progressive fibrosis remains a significant medical problem ...
Jolanta Fertala +6 more
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Cancer Extracellular Matrix Proteins Regulate Tumour Immunity [PDF]
Cancers, 2020 The extracellular matrix (ECM) plays an increasingly recognised role in the development and progression of cancer. Whilst significant progress has been made in targeting aspects of the tumour microenvironment such as tumour immunity and angiogenesis, there are no therapies that address the cancer ECM.
Alex Gordon-Weeks, Arseniy Yuzhalin
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The functional role of soluble proteins acquired by extracellular vesicles
Journal of Extracellular Biology, 2022 Extracellular vesicles (EVs) are lipid bilayer‐enclosed nanosized particles released by all cell types during physiological as well as pathophysiological processes to carry out diverse biological functions, including acting as sources of cellular dumping,
Ana Paula Ramos +7 more
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Natural biopolymer-based hydrogels as designer matrices for organoid cultures [PDF]
Organoid, 2023 Matrigel, a mouse sarcoma-derived extract, is considered the gold standard for organoid cultures. However, it has several drawbacks, including inconsistent and ill-defined composition, varying quality between batches, and potential cancer-related health ...
Yun Kee Jo
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ECM1 (extracellular matrix protein 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2017 Review on the ECM1 ...
Gomez-Contreras, Piedad C, Lal, Geeta
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