Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli [PDF]
BMC Nephrology, 2019 Background IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN.
Flavia Teodora Ioana Paunas +6 more
doaj +3 more sources
Identification of biofilm proteins in non-typeable
BMC Microbiology, 2006 Background Non-typeable Haemophilus influenzae biofilm formation is implicated in a number of chronic infections including otitis media, sinusitis and bronchitis.
Aguilera Rodrigo +3 more
doaj +4 more sources
Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells [PDF]
Respiratory Research, 2006 Background Tracheal epithelial cells are anchored to a dynamic basement membrane that contains a variety of extracellular matrix proteins including collagens and laminins. During development, wound repair and disease of the airway epithelium, significant
Olsen Colin E +2 more
doaj +4 more sources
Thin films of Type 1 collagen for cell by cell analysis of morphology and tenascin-C promoter activity [PDF]
BMC Biotechnology, 2006 Background The use of highly reproducible and spatiallyhomogeneous thin film matrices permits automated microscopy and quantitative determination of the response of hundreds of cells in a population.
Tona Alex +4 more
doaj +4 more sources
Development potential of extracellular matrix hydrogels as hemostatic materials
Frontiers in Bioengineering and Biotechnology, 2023 The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular matrix proteins are unable to cover the wound, making it ...
Dan Cai, Wei Weng
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 The absence or damage of a tissue is the main cause of most acute or chronic diseases and are one of the appealing challenges that novel therapeutic alternatives have, in order to recover lost functions through tissue regeneration.
Víctor Alfonso Solarte David +6 more
doaj +1 more source
Extracellular Targets to Reduce Excessive Scarring in Response to Tissue Injury
Biomolecules, 2023 Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite extensive studies to define valid anti-fibrotic targets and develop effective therapeutics, progressive fibrosis remains a significant medical problem ...
Jolanta Fertala +6 more
doaj +1 more source
The functional role of soluble proteins acquired by extracellular vesicles
Journal of Extracellular Biology, 2022 Extracellular vesicles (EVs) are lipid bilayer‐enclosed nanosized particles released by all cell types during physiological as well as pathophysiological processes to carry out diverse biological functions, including acting as sources of cellular dumping,
Ana Paula Ramos +7 more
doaj +1 more source
The Constitutive Extracellular Protein Release by Acute Myeloid Leukemia Cells—A Proteomic Study of Patient Heterogeneity and Its Modulation by Mesenchymal Stromal Cells [PDF]
, 2021 Extracellular protein release is important both for the formation of extracellular matrix and for communication between cells. We investigated the extracellular protein release by in vitro cultured normal mesenchymal stem cells (MSCs) and by primary ...
Aasebø, Elise +6 more
core +1 more source
Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity
Scientific Reports, 2021 Obesity and the metabolic disease epidemic has led to an increase in morbidity and mortality. A rise in adipose thermogenic capacity via activation of brown or beige fat is a potential treatment for metabolic diseases.
Maria A. Gonzalez Porras +10 more
doaj +1 more source