Syndecan-2 is a novel target of insulin-like growth factor binding protein-3 and is over-expressed in fibrosis [PDF]
, 2012 Extracellular matrix deposition and tissue scarring characterize the process of fibrosis. Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 (IGFBP-3) have been implicated in the pathogenesis of fibrosis in various ...
Adriana T. Larregina +7 more
core +8 more sources
Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain [PDF]
, 1999 Increasing evidence indicates that tissue transglutaminase (tTG) plays a role in the assembly and remodeling of extracellular matrices and promotes cell adhesion.
Aeschlimann, D +5 more
core +1 more source
Journal of Tissue Engineering, 2020 Recently, extracellular matrix-based tissue-engineered bone is a promising approach to repairing bone defects, and the seed cells are mostly mesenchymal stem cells.
Rui Dong +9 more
doaj +1 more source
A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]
, 2015 Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin +5 more
core +2 more sources
mBio, 2014 Biofilm formation by Staphylococcus aureus involves the formation of an extracellular matrix, but the composition of this matrix has been uncertain. Here we report that the matrix is largely composed of cytoplasmic proteins that reversibly associate with
Lucy Foulston +3 more
doaj +1 more source
Stepwise Evolution of Coral Biomineralization Revealed with Genome-Wide Proteomics and Transcriptomics. [PDF]
PLoS ONE, 2016 Despite the importance of stony corals in many research fields related to global issues, such as marine ecology, climate change, paleoclimatogy, and metazoan evolution, very little is known about the evolutionary origin of coral skeleton formation.
Takeshi Takeuchi +4 more
doaj +1 more source
Extracellular matrix proteins involved in pseudoislets formation [PDF]
Islets, 2009 Extracellular matrix proteins are known to mediate, through integrins, cell adhesion and are involved in a number of cellular processes, including insulin expression and secretion in pancreatic islets. We investigated whether expression of some extracellular matrix proteins were implied in islets-like structure formation, named pseudoislets.
Maillard, Elisa +6 more
openaire +2 more sources
Importance of geometry of the extracellular matrix in endochondral bone differentiation. [PDF]
, 1984 Subcutaneous implantation of coarse powders (74-420 micron) of demineralized diaphyseal bone matrix resulted in the local differentiation of endochondral bone.
Reddi, AH, Sampath, TK
core +1 more source
A view of the genetic and proteomic profile of extracellular matrix molecules in aging and stroke
Frontiers in Cellular Neuroscience, 2023 IntroductionModification of the extracellular matrix (ECM) is one of the major processes in the pathology of brain damage following an ischemic stroke.
Martina Chmelova +10 more
doaj +1 more source
Fluorescent protein markers to tag collagenous proteins: The paradigm of procollagen VII [PDF]
, 2009 Fluorescent proteins are powerful markers allowing tracking expression, intracellular localization, and translocation of tagged proteins but their effects on the structure and assembly of complex extracellular matrix proteins has not been investigated ...
Chung, Hye J. +3 more
core +2 more sources