Results 31 to 40 of about 866,232 (334)

A novel chemotactic factor derived from the extracellular matrix protein decorin recruits mesenchymal stromal cells in vitro and in vivo.

open access: yesPLoS ONE, 2020
Soft tissue is composed of cells surrounded by an extracellular matrix that is made up of a diverse array of intricately organized proteins. These distinct components work in concert to maintain homeostasis and respond to tissue damage.
Sandi Grainne Dempsey   +5 more
doaj   +1 more source

Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]

open access: yesPLoS ONE, 2014
Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi   +4 more
doaj   +1 more source

DeepECMP: Predicting Extracellular Matrix Proteins using Deep Learning [PDF]

open access: yesarXiv, 2021
Introduction: The extracellular matrix (ECM) is a networkof proteins and carbohydrates that has a structural and bio-chemical function. The ECM plays an important role in dif-ferentiation, migration and signaling. Several studies havepredicted ECM proteins using machine learning algorithmssuch as Random Forests, K-nearest neighbours and supportvector ...
arxiv  

The extracellular matrix: Structure, composition, age-related differences, tools for analysis and applications for tissue engineering

open access: yesJournal of Tissue Engineering, 2014
The extracellular matrix is a structural support network made up of diverse proteins, sugars and other components. It influences a wide number of cellular processes including migration, wound healing and differentiation, all of which is of particular ...
Jaspreet K Kular   +2 more
doaj   +1 more source

Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix

open access: yesmBio, 2019
We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms.
Jeffrey S. Kavanaugh   +9 more
doaj   +1 more source

A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]

open access: yes, 2015
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin   +5 more
core   +2 more sources

Shotgun Proteomics and Network Analysis between Plasma Membrane and Extracellular Matrix Proteins from Rat Olfactory Ensheathing Cells

open access: yesCell Transplantation, 2010
Olfactory ensheathing cells (OECs) are a special type of glial cells that have characteristics of both astrocytes and Schwann cells. Evidence suggests that the regenerative capacity of OECs is induced by soluble, secreted factors that influence their ...
Yisong Liu   +15 more
doaj   +1 more source

Recent Advances and Prospects in the Research of Nascent Adhesions [PDF]

open access: yes, 2020
Nascent adhesions are submicron transient structures promoting the early adhesion of cells to the extracellular matrix. Nascent adhesions typically consist of several tens of integrins, and serve as platforms for the recruitment and activation of proteins to build mature focal adhesions.
arxiv   +1 more source

The Role of Cell-Matrix Interactions in Connective Tissue Mechanics [PDF]

open access: yes, 2021
Living tissue is able to withstand large stresses in everyday life, yet it also actively adapts to dynamic loads. This remarkable mechanical behaviour emerges from the interplay between living cells and their non-living extracellular environment. Here we review recent insights into the biophysical mechanisms involved in the reciprocal interplay between
arxiv   +1 more source

How bacteria hack the matrix and dodge the bullets of immunity

open access: yesEuropean Respiratory Review, 2018
Haemophilus influenzae, Moraxella catarrhalis and Pseudomonas aeruginosa are common Gram-negative pathogens associated with an array of pulmonary diseases. All three species have multiple adhesins in their outer membrane, i.e.
Magnus Paulsson, Kristian Riesbeck
doaj   +1 more source

Home - About - Disclaimer - Privacy