Results 71 to 80 of about 866,232 (334)

Immunohistochemical Detection of Various Proteoglycans in the Extracellular Matrix of Zebra Mussels

open access: yesFishes, 2022
Mussels have been used as animal models for studying ecotoxicology, biomineralization, and bio-adhesion for many years. Despite a wealth of studies on their shell matrix and byssus proteins, few studies have focused on the extracellular matrix molecules ...
Wenkai Wu   +5 more
doaj   +1 more source

Clustering of lipids driven by integrin [PDF]

open access: yesarXiv, 2022
Integrin is an important transmembrane receptor protein which remodels the actin network and anchors the cell membrane towards the extracellular matrix via mechanochemical pathways. The clustering of specific lipids and lipid-anchored proteins, which is essential for a certain type of endocytosis process, is facilitated at integrin-mediated active ...
arxiv  

The Extracellular Matrix Complexome from Skeletal Muscle [PDF]

open access: yes, 2016
The various layers of the extracellular matrix, forming the endomysium, perimysium and epimysium of skeletal muscles, provide essential structural and mechanical support to contractile fibres.
Murphy, Sandra, Ohlendieck, Kay
core   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

The effects and mechanisms of extracellular matrix proteins on congenital tooth malformation

open access: yes生物医学转化, 2023
Congenital tooth developmental anomalies refer to a type of tooth disease where the shape or structure of the teeth is abnormal during embryonic development or after birth.
Yang Haoqing, Fan Zhipeng
doaj   +1 more source

Neuron Growth Output-Feedback Control by PDE Backstepping [PDF]

open access: yesarXiv, 2022
Neurological injuries predominantly result in loss of functioning of neurons. These neurons may regain function after particular medical therapeutics, such as Chondroitinase ABC (ChABC), that promote axon elongation by manipulating the extracellular matrix, the network of extracellular macromolecules, and minerals that control the tubulin protein ...
arxiv  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Regulation of pituitary hormones and cell proliferation by components of the extracellular matrix

open access: yesBrazilian Journal of Medical and Biological Research, 2005
The extracellular matrix is a three-dimensional network of proteins, glycosaminoglycans and other macromolecules. It has a structural support function as well as a role in cell adhesion, migration, proliferation, differentiation, and survival.
M. Paez-Pereda   +3 more
doaj   +1 more source

Exploring bioinformatics tools and databases to decipher the proteome of Candida glabrata biofilm matrix [PDF]

open access: yes, 2021
Candida glabrata is a clinically relevant human pathogen with ability to form high recalcitrant biofilms, which produce an extracellular matrix suggested to have structural, virulent and protective roles.
Gonçalves, Bruna, Silva, Sónia Carina
core  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

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