Results 61 to 70 of about 659,606 (256)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Cell death and respiration inhibition of tobacco suspension cells under NaCl stress may be mediated by extracellular ATP

四川大学学报. 自然科学版, 2017
In the present work, by using BY-2 tobacco suspension cells, the effect of the extracellular ATP on the cell death and respiration inhibition induced by NaCl stress was studied.
BAI Jing-Yue, FENG Han-Qing, RONG Fu-Hu, LU Li-Na, WANG Qing-Wen, JIA Ling-Yun   +5 more
doaj  

Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II

Redox Biology, 2016
Nitro-fatty acids (NO2-FA) are metabolic and inflammatory-derived electrophiles that mediate pleiotropic signaling actions. It was hypothesized that NO2-FA would impact mitochondrial redox reactions to induce tissue-protective metabolic shifts in cells ...
Jeffrey R. Koenitzer, Gustavo Bonacci, Steven R. Woodcock, Chen-Shan Chen, Nadiezhda Cantu-Medellin, Eric E. Kelley, Francisco J. Schopfer   +6 more
doaj   +1 more source

Factors controlling spatio-temporal variation in carbon dioxide efflux from surface litter, roots, and soil organic matter at four rain forest sites in the eastern Amazon [PDF]

, 2007
This study explored biotic and abiotic causes for spatio-temporal variation in soil respiration from surface litter, roots, and soil organic matter over one year at four rain forest sites with different vegetation structures and soil types in the eastern
da Costa, A. C. L., de Almeida, S. S., Meir, P., Aragao, L. E. O. C., Braga, A., de Athaydes, J., Metcalfe, D. B., Malhi, Y., Williams, M.; id_orcid, Goncalves, P. H. L.   +9 more
core   +1 more source

Respiration-induced modulation of global field power.

, 2021
(A) Exemplary schematic of our analysis approach showing the wavelet transform of time series data from each voxel. Global field power was computed on the time course of all 268 channels for further analyses of the MI and PTA.
Joachim Gross (220911), Daniel S. Kluger (5979131)   +1 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Non‐Respiratory Extracellular Electron Transfer Competes with Nitrogenase for Electrons in Rhodopseudomonas Palustris

Advanced Science
Biological nitrogen fixation (BNF) is a pivotal process that reduces nitrogen to ammonium within the nitrogen cycle. Extracellular electron transfer (EET) between diazotrophs and the extracellular environment influences the occurrence and efficiency of ...
Xuewen Liu, Panqing Qi, Weipeng Fan, Wuyang Liu, Xingjiang Li, Yong Nie, Xiao‐Lei Wu   +6 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source