Results 71 to 80 of about 169,199 (298)

Widespread depolarization during expiration: A source of respiratory drive? [PDF]

open access: yes, 2014
Respiration influences various pacemakers and rhythms of the body during inspiration and expiration but the underlying mechanisms are relatively unknown.
Barnes, Vernon A.   +3 more
core  

Peatlands and the carbon cycle: from local processes to global implications - a synthesis [PDF]

open access: yes, 2008
Peatlands cover only 3% of the Earth's land surface but boreal and subarctic peatlands store about 15-30% of the world's soil carbon ( C) as peat. Despite their potential for large positive feedbacks to the climate system through sequestration and ...
Berendse, F.   +8 more
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Site Of The Activity Of Extracellular Products Of Pseudomonas Aeruginosa In The Electron-Transport Chain In Mammalian Cell Respiration [PDF]

open access: yesJournal of Medical Microbiology, 1971
Summary Since 1-hydroxyphenazine derived from Pseudomonas aeruginosa or chemically synthesised inhibited the uptake of oxygen by mouse liver mitochondria utilising sodium succinate, attempts were made to determine the site of activity in the electron transport chain.
A V, Armstrong, D E, Stewart-Tull
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II

open access: yesRedox Biology, 2016
Nitro-fatty acids (NO2-FA) are metabolic and inflammatory-derived electrophiles that mediate pleiotropic signaling actions. It was hypothesized that NO2-FA would impact mitochondrial redox reactions to induce tissue-protective metabolic shifts in cells ...
Jeffrey R. Koenitzer   +6 more
doaj   +1 more source

Cysteine-Mediated Extracellular Electron Transfer of Lysinibacillus varians GY32

open access: yesMicrobiology Spectrum, 2022
Microbial extracellular electron transfer (EET) is essential in many natural and engineering processes. Compared with the versatile EET pathways of Gram-negative bacteria, the EET of Gram-positive bacteria has been studied much less and is mainly limited
Guannan Kong   +9 more
doaj   +1 more source

Factors affecting pH change in alkaline waste water treatment - II: Carbon dioxide production [PDF]

open access: yes, 1971
The carbon dioxide produced during biological oxidation of wastewater has a pronounced influence upon the pH that is attained in the activated sludge process.
Lijklema, L.
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

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