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Potential of extracellular space for tissue regeneration in dentistry [PDF]

open access: yesFrontiers in Physiology, 2022
With the proven relationship between oral and general health and the growing aging population, it is pivotal to provide accessible therapeutic approaches to regenerate oral tissues and restore clinical function.
Anahid A. Birjandi, Paul Sharpe
doaj   +2 more sources

Mechanism of extracellular space changes in cryptococcal brain granuloma revealed by MRI tracer [PDF]

open access: yesFrontiers in Neuroscience, 2022
PurposeThis study aimed to investigate the changes in extracellular space (ECS) in cryptococcal brain granuloma and its pathological mechanism.Materials and methodsThe animal model of cryptococcal brain granuloma was established by injecting 1 × 106 CFU ...
Nuerbiyemu Abulikemu   +25 more
doaj   +2 more sources

Changes in diffusion through the brain extracellular space [PDF]

open access: green, 2004
ECS (extracellular space) works as the microenvironment of brain cells. Diffusion through ECS may be described through an effective diffusion coefficient, De, which in turn depends on ECS porosity, ε, and tortuosity, T. In the present research, diffusion
М. Мота   +3 more
openalex   +5 more sources

Nanoscale and functional heterogeneity of the hippocampal extracellular space

open access: yesCell Reports, 2023
Summary: The extracellular space (ECS) and its constituents play a crucial role in brain development, plasticity, circadian rhythm, and behavior, as well as brain diseases.
Diego Grassi   +7 more
doaj   +2 more sources

Current Techniques for Investigating the Brain Extracellular Space [PDF]

open access: yesFrontiers in Neuroscience, 2020
The brain extracellular space (ECS) is a continuous reticular compartment that lies between the cells of the brain. It is vast in extent relative to its resident cells, yet, at the same time the nano- to micrometer dimensions of its channels and ...
Federico N. Soria   +6 more
doaj   +2 more sources

Local diffusion in the extracellular space of the brain

open access: goldNeurobiology of Disease, 2023
The brain extracellular space (ECS) is a vast interstitial reticulum of extreme morphological complexity, composed of narrow gaps separated by local expansions, enabling interconnected highways between neural cells.
Jan Tønnesen   +2 more
doaj   +2 more sources

Imaging of the Entry Pathway of a Cell-Penetrating Peptide–DNA Complex From the Extracellular Space to Chloroplast Nucleoids Across Multiple Membranes in Arabidopsis Leaves [PDF]

open access: yesFrontiers in Plant Science, 2021
Each plant cell has hundreds of copies of the chloroplast genome and chloroplast transgenes do not undergo silencing. Therefore, chloroplast transformation has many powerful potential agricultural and industrial applications.
Kazusato Oikawa   +6 more
doaj   +2 more sources

Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space [PDF]

open access: yeseLife, 2020
Neurons in developing sensory pathways exhibit spontaneous bursts of electrical activity that are critical for survival, maturation and circuit refinement.
Travis A Babola   +3 more
doaj   +2 more sources

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling [PDF]

open access: yesNature Communications, 2020
The nanoscale organisation of the brain extracellular space can be studied in vivo. Here, the authors investigate how it changes in response to α-synuclein pathology, and identify interactions between microglia and the extracellular matrix.
Federico N. Soria   +11 more
doaj   +2 more sources

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