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Current Techniques for Investigating the Brain Extracellular Space [PDF]

open access: yesFrontiers in Neuroscience, 2020
The brain extracellular space (ECS) is a continuous reticular compartment that lies between the cells of the brain. It is vast in extent relative to its resident cells, yet, at the same time the nano- to micrometer dimensions of its channels and ...
Federico N. Soria   +6 more
doaj   +7 more sources

Protein Dynamics in the Plant Extracellular Space [PDF]

open access: yesProteomes, 2016
The extracellular space (ECS or apoplast) is the plant cell compartment external to the plasma membrane, which includes the cell walls, the intercellular space and the apoplastic fluid (APF).
Leonor Guerra-Guimarães   +4 more
doaj   +7 more sources

Diffusion in Brain Extracellular Space [PDF]

open access: greenPhysiological Reviews, 2008
Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction and the tortuosity and a modified diffusion equation represents the transport behavior of many molecules in the brain. Deviations from the equation reveal loss of molecules across the blood-brain barrier, through cellular uptake, binding, or other mechanisms ...
Eva Syková, Charles Nicholson
semanticscholar   +5 more sources

Nanoscale and functional heterogeneity of the hippocampal extracellular space

open access: yesCell Reports, 2023
Summary: The extracellular space (ECS) and its constituents play a crucial role in brain development, plasticity, circadian rhythm, and behavior, as well as brain diseases.
Diego Grassi   +7 more
doaj   +5 more sources

Potential of extracellular space for tissue regeneration in dentistry [PDF]

open access: yesFrontiers in Physiology, 2022
With the proven relationship between oral and general health and the growing aging population, it is pivotal to provide accessible therapeutic approaches to regenerate oral tissues and restore clinical function.
Anahid A. Birjandi, Paul Sharpe
doaj   +2 more sources

Mechanism of extracellular space changes in cryptococcal brain granuloma revealed by MRI tracer [PDF]

open access: yesFrontiers in Neuroscience, 2022
PurposeThis study aimed to investigate the changes in extracellular space (ECS) in cryptococcal brain granuloma and its pathological mechanism.Materials and methodsThe animal model of cryptococcal brain granuloma was established by injecting 1 × 106 CFU ...
Nuerbiyemu Abulikemu   +25 more
doaj   +2 more sources

The Extracellular Space of Voluntary Muscle Tissues [PDF]

open access: bronzeThe Journal of General Physiology, 1967
The volume occupied by the extracellular space has been investigated in six types of voluntary muscles: sartorius (frog), semitendinosus (frog), tibialis anticus longus (frog), iliofibularis (frog), rectus abdominis (frog), and diaphragm (rat). With the aid of four types of probe material, three of which are conventionally employed (inulin, sorbitol ...
Gilbert N. Ling, Marsha H. Kromash
openalex   +5 more sources

Determination of Extracellular Space in Amphibian Muscle [PDF]

open access: bronzeThe Journal of General Physiology, 1967
The volumes of distribution of inulin and dextran in the sartorius, stomach, and cardiac muscle of the frog agree rather closely. That these spaces represent the volume of extracellular water is supported by the observation that efflux of sucrose can be divided into a fast and a slow phase and that the fast-moving fraction corresponds closely with ...
Emil Bozler
openalex   +5 more sources

Electrodiffusive model for astrocytic and neuronal ion concentration dynamics. [PDF]

open access: yesPLoS Computational Biology, 2013
The cable equation is a proper framework for modeling electrical neural signalling that takes place at a timescale at which the ionic concentrations vary little.
Geir Halnes   +4 more
doaj   +2 more sources

Modeling extracellular field potentials and the frequency-filtering properties of extracellular space [PDF]

open access: yesBiophysics Journal 86 (2004) 1829-1842, 2003
Extracellular local field potentials (LFP) are usually modeled as arising from a set of current sources embedded in a homogeneous extracellular medium. Although this formalism can successfully model several properties of LFPs, it does not account for their frequency-dependent attenuation with distance, a property essential to correctly model ...
Bédard, Claude   +2 more
arxiv   +7 more sources

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