Results 1 to 10 of about 2,515 (118)
Protein Dynamics in the Plant Extracellular Space [PDF]
Proteomes, 2016 The extracellular space (ECS or apoplast) is the plant cell compartment external to the plasma membrane, which includes the cell walls, the intercellular space and the apoplastic fluid (APF).
Leonor Guerra-Guimarães +4 more
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An Isotonic Model of Neuron Swelling Based on Co-Transport of Salt and Water
Membranes, 2023 Neurons spend most of their energy building ion gradients across the cell membrane. During energy deprivation the neurons swell, and the concomitant mixing of their ions is commonly assumed to lead toward a Donnan equilibrium, at which the concentration ...
Reinoud Maex
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Potential of extracellular space for tissue regeneration in dentistry
Frontiers in Physiology, 2022 With the proven relationship between oral and general health and the growing aging population, it is pivotal to provide accessible therapeutic approaches to regenerate oral tissues and restore clinical function.
Anahid A. Birjandi, Paul Sharpe
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New Insights into Alzheimer’s Disease: Novel Pathogenesis, Drug Target and Delivery
Pharmaceutics, 2023 Alzheimer’s disease (AD), the most common type of dementia, is characterized by senile plaques composed of amyloid β protein (Aβ) and neurofilament tangles derived from the hyperphosphorylation of tau protein.
Haishu Chen +7 more
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Unconventional Pathways of Protein Secretion: Mammals vs. Plants
Frontiers in Cell and Developmental Biology, 2022 In eukaryotes, many proteins contain an N-terminal signal peptide that allows their translocation into the endoplasmic reticulum followed by secretion outside the cell according to the classical secretory system. However, an increasing number of secreted
Elisa Maricchiolo +5 more
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Frontiers in Oncology, 2023 ObjectivesTo evaluate whether tumor extracellular volume fraction (fECV) on contrast-enhanced computed tomography (CT) aids in the differentiation between intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC).MethodsIn this ...
T. Honda +12 more
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Frontiers in Neurology, 2021 Interictal spikes (IISs) may result from a disturbance of the intimate functional balance between various neuronal (synaptic and non-synaptic), vascular, and metabolic compartments.
Cristian Arnal-Real +4 more
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Mechanism of extracellular space changes in cryptococcal brain granuloma revealed by MRI tracer
Frontiers in Neuroscience, 2022 PurposeThis study aimed to investigate the changes in extracellular space (ECS) in cryptococcal brain granuloma and its pathological mechanism.Materials and methodsThe animal model of cryptococcal brain granuloma was established by injecting 1 × 106 CFU ...
Nuerbiyemu Abulikemu +25 more
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Diffusion in Brain Extracellular Space [PDF]
Physiological Reviews, 2008 Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction and the tortuosity and a modified diffusion equation represents the transport behavior of many molecules in the brain. Deviations from the equation reveal loss of molecules across the blood-brain barrier, through cellular uptake, binding, or other mechanisms ...
Eva, Syková, Charles, Nicholson
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The Lysosomal Sequestration of Tyrosine Kinase Inhibitors and Drug Resistance
Biomolecules, 2019 The Lysosomal sequestration of weak-base anticancer drugs is one putative mechanism for resistance to chemotherapy but it has never been directly proven. We addressed the question of whether the lysosomal sequestration of tyrosine kinase inhibitors (TKIs)
Eliska Ruzickova +4 more
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