In Vitro Assessment of Factors Affecting the Apparent Diffusion Coefficient of Ramos Cells Using Bio-phantoms [PDF]
The roles of cell density, extracellular space, intracellular factors, and apoptosis induced by the molecularly targeted drug rituximab on the apparent diffusion coefficient (ADC) values were investigated using bio-phantoms.
Asaumi, Junichi+9 more
core +1 more source
Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]
Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Dale, Nicholas+3 more
core +2 more sources
Macrophages have a vital role in the immune system through elimination of cell debris and microorganisms by phagocytosis. The activation of macrophages by tumour necrosis factor-α induces expression of extracellular cell-surface vimentin and promotes ...
Divyendu Goud Thalla+6 more
doaj +1 more source
Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis [PDF]
BackgroundAtopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation.
Barton, Geoffrey J.+10 more
core +3 more sources
Formation of Extracellular Traps - the Effective Mechanism of Organism Protection from Pathogen
Summarized and analyzed are modern literature data on capability of cells (neutrophils, eosinophils and labrocytes) realizing the mechanisms of innate immunity, to form extracellular traps that capture and kill pathogens by secretion of DNA and ...
A. L. Kravtsov
doaj +1 more source
Extracellular cysteine in connexins: Role as redox sensors [PDF]
Indexación: Scopus.Connexin-based channels comprise hemichannels and gap junction channels. The opening of hemichannels allow for the flux of ions and molecules from the extracellular space into the cell and vice versa.
Báez, D.+7 more
core +2 more sources
Viruses on the Move in the Extracellular Space [PDF]
Positive-strand (+) RNA viruses act as their own messengers, encoding an RNA-dependent RNA polymerase that can replicate their sense RNA genome. This allows (+) RNA viruses to replicate outside the nucleus, within replication complexes formed from host organelle membranes often called ...
openaire +3 more sources
Objective. To study the response of volume and osmoregulatory kidney function to increased volume of extracellular space (IVECS) with dopamine-dependent compensation of sepsis-induced hypotension. Materials and methods. The inclusion criteria involved
V. M. Konovchuk, A. V. Andrushchak
doaj +1 more source
Leaf apoplastic proteome composition in UV-B treated Arabidopsis thaliana mutants impaired in extracellular glutathione degradation [PDF]
In plants, environmental perturbations often result in oxidative reactions in the apoplastic space, which are counteracted for by enzymatic and non-enzymatic antioxidative systems, including ascorbate and glutathione. The occurrence of the latter and its
Arrigoni, Giorgio+2 more
core +1 more source
Exploring the Dynamics of Brain Extracellular Space. [PDF]
Pajevic S.
europepmc +5 more sources