Results 51 to 60 of about 5,853,415 (367)

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

eLife, 2017
Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that ...
Alex J Smith, Xiaoming Yao, James A Dix, Byung-Ju Jin, Alan S Verkman   +4 more
doaj   +1 more source

Altered Tracer Distribution and Clearance in the Extracellular Space of the Substantia Nigra in a Rodent Model of Parkinson's Disease

Frontiers in Neuroscience, 2017
The relationship between extracellular space (ECS) diffusion parameters and brain drug clearance is not well-studied, especially in the context of Parkinson's disease (PD). Therefore, we used a rodent model of PD to explore the distribution and clearance
Yuan Fang, Yanchao Dong, Tao Zheng, Dan Du, Jiexia Wen, Dawei Gao, Lanxiang Liu   +6 more
doaj   +1 more source

Formation of Extracellular Traps - the Effective Mechanism of Organism Protection from Pathogen

Проблемы особо опасных инфекций, 2012
Summarized and analyzed are modern literature data on capability of cells (neutrophils, eosinophils and labrocytes) realizing the mechanisms of innate immunity, to form extracellular traps that capture and kill pathogens by secretion of DNA and ...
A. L. Kravtsov
doaj   +1 more source

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response. [PDF]

, 2013
BackgroundTraumatic brain injury (TBI) results in irreversible damage at the site of impact and initiates cellular and molecular processes that lead to secondary neural injury in the surrounding tissue.
Ford, Byron D, Ford, Gregory D, Gates, Alicia S, Laplaca, Michelle C, Surles-Zeigler, Monique C, White, Todd E   +5 more
core   +2 more sources

Unveiling the Extracellular Space of the Brain: From Super-resolved Microstructure to In Vivo Function

Journal of Neuroscience, 2018
The extracellular space occupies approximately one-fifth of brain volume, molding a spider web of gaps filled with interstitial fluid and extracellular matrix where neurons and glial cells perform in concert.
S. Hrabetova, Laurent Cognet, Laurent Cognet, D. Rusakov, U. V. Nägerl   +4 more
semanticscholar   +1 more source

The Association of Heart Failure and Liver T1 Mapping in Cardiac Magnetic Resonance Imaging

Diagnostics
Background/Objectives: The objective of this study was to investigate the association between congestive heart failure (CHF) and T1 mapping in both liver lobes using cardiac MRI.
Adrian T. Huber, Joanna Bartkowiak, Robin Seitz, Benedikt Bernhard, Martina Boscolo Berto, Giancarlo Spano, Benedikt Wagner, Verena C. Obmann, Lukas Ebner, Inga A. S. Todorski, Michael P. Brönnimann, Kady Fischer, Dominik P. Guensch, Andreas Christe, Annalisa Berzigotti, Lorenz Räber, Tobias Reichlin, Thomas Pilgrim, Fabien Praz, Christoph Gräni, Nicholas Brugger, Alan A. Peters   +21 more
doaj   +1 more source

Studying the extracellular contribution to the double wave vector diffusion-weighted signal

Current Directions in Biomedical Engineering, 2015
The use of two independent diffusion periods between excitation and acquisition, known as double wave vector (DWV) diffusion-weighting or double diffusion encoding, was proven to yield structural information that it is otherwise not easily available in ...
Ulloa Patricia, Wottschel Viktor, Koch Martin A.   +2 more
doaj   +1 more source

Gastropod-derived haemocyte extracellular traps entrap metastrongyloid larval stages of Angiostrongylus vasorum, Aelurostrongylus abstrusus and Troglostrongylus brevior [PDF]

, 2017
Background: Phagocyte-derived extracellular traps (ETs) were recently demonstrated mainly in vertebrate hosts as an important effector mechanism against invading parasites.
Gärtner, Ulrich, Hermosilla, Carlos, Lange, Malin K., Mejer, Helena, Muñoz-Caro, Tamara, Penagos-Tabares, Felipe, Schaper, Roland, Taubert, Anja   +7 more
core   +4 more sources

Effective Extracellular Volume Fraction Determined by Equilibrium Contrast-Enhanced CT for Differentiating Autoimmune Pancreatitis from Pancreatic Ductal Adenocarcinoma

Diagnostics
Background/Objectives: The aim of this study was to determine whether extracellular volume (ECV) fraction as determined by contrast-enhanced computed tomography (CECT) can help distinguish between autoimmune pancreatitis (AIP) and pancreatic ductal ...
Akihiko Kanki, Yoshihiko Fukukura, Hidemitsu Sotozono, Kiyoka Maeba, Atsushi Higaki, Yuki Sato, Akira Yamamoto, Ryo Moriwake, Tsutomu Tamada   +8 more
doaj   +1 more source

Intracellular impedance measurements reveal non-ohmic properties of the extracellular medium around neurons

, 2015
The electrical properties of extracellular space around neurons are important to understand the genesis of extracellular potentials, as well as for localizing neuronal activity from extracellular recordings.
Bal, Thierry, Bedard, Claude, Destexhe, Alain, Gomes, Jean-Marie, Khokhlova, Vitalia, Nelson, Matthew, Pouget, Pierre, Valtcheva, Silvana, Venance, Laurent   +8 more
core   +2 more sources